Faculty

Carrie A. Schinstock, M.D.

Clinical Studies

A Pivotal Phase 3 Trial to Evaluate the Safety and Efficacy of Clazakizumab for the Treatment of Chronic Active Antibody-mediated Rejection in Kidney Transplant Recipients (IMAGINE) Rochester, Minn., Scottsdale/Phoenix, Ariz.
The purpose of this study is to investigate whether clazakizumab (an anti-interleukin (IL)-6 monoclonal antibody (mAb)) may be beneficial for the treatment of CABMR in recipients of a kidney transplant by inhibiting the production of Donor Specific Antibodies (DSA) and re-shaping T cell alloimmune responses.

Analysis of Urinary Exosomes in Healthy Kidney Donors and Renal Transplant Recipients Rochester, Minn.
The purpose of this study is to use urinary exosomes to non-invasively identify (protein biomarkers) various conditions affecting the renal transplant.

Alloimmune T-Cell Responses in Highly Sensitized Kidney Transplant Recipients: A Pilot Study Rochester, Minn., Scottsdale/Phoenix, Ariz.
The purpose of this study is to better understand how the immune system reacts to kidney transplantation in individuals who are potentially at higher risk for rejection.