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  • Alloimmune T-Cell Responses in Highly Sensitized Kidney Transplant Recipients: A Pilot Study Rochester, Minn., Scottsdale/Phoenix, Ariz.

    The purpose of this study is to better understand how the immune system reacts to kidney transplantation in individuals who are potentially at higher risk for rejection.

  • Identifying Physical Function Trajectories and Biomarkers after Kidney Transplantation Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz.

    The aims of this study are to identify frailty trajectories and biomarkers of frailty after kidney transplantation. Subjects will be followed beginning immediately prior to kidney transplantation until 1 year after kidney transplantation. Frailty will be prospectively assessed using performance-based measures (Fried criteria and Short Physical Impairment Battery). The relationship between frailty measures and blood levels of promising candidate biomarkers will be analyzed.