Rahul Pannala, M.D.

The purpose of this study is to compare the two approaches for monitoring pancreatic cysts - more frequent monitoring vs. less frequent monitoring in order to learn which monitoring method leads to better outcome for patients with pancreatic cysts.

The purpose of this study is to evaluate EUS-nCLE as an imaging biomarker and PCL fluid DNA analysis as a molecular biomarker for the management of pancreatic cystic lesions (PCLs).

This initial (pilot) study proposes to follow glycemic control, sleep and activity dynamics of individuals without diabetes identified for initiation of GLP-1 agonists/ GLP-1/GIP agonists from before the start of medication treatment to six months after in an effort to identify the predictors of treatment success. Glycemic control will be monitored using the Ultrahuman M1(UH-M1) continuous glucose monitoring system, while sleep and activity will be measured by the Ultrahuman Ring AIR (UH-RA) on the same user interface. It is proposed that participants will wear the devices for a period of 28 days before the initiation of GLP-1 agonists and up to 12 months post-initiation follow up. A variety of glucose data, heart rate, activity indices will be gathered and tracked through the study period to identify metrics that correlate the most with treatment success.

Thr purpose of this study is to create a database of clinical information and a repository of biological specimens for genetic, molecular and microbiological research to better understand obesity and changes with treatment to more accurately predict the outcomes of endobariatric and other therapies and to help develop new therapies.

The purpose of this study is to compare the two approaches for monitoring pancreatic cysts - more frequent monitoring vs. less frequent monitoring in order to learn which monitoring method leads to better outcome for patients with pancreatic cysts.

The purpose of this study is to assess the effectiveness of Revita® DMR for improving HbA1c to ≤ 7% without the need of insulin in subjects with T2D compared to sham and to assess the effectiveness of DMR versus Sham on improvement in Glycemic, Hepatic and Cardiovascular endpoints.

The purpose of this study is to investigate if Hybrid Argon Plasma Coagulation (HAPC) is non-inferior to Radiofrequency Ablation (RFA) in the stricture-free eradication of the dysplastic Barrett's Esophagus (BE) epithelium.

The purpose of this study is to assess DNA markers in pancreatic juice and stool for the detection of pancreatic cancer and precancer.

The purpose of this study is to prospectively evaluate the safety and effectiveness of standard of care, individualized, comprehensive weight loss interventions in carefully selected patients with obesity undergoing liver transplant evaluation, including utilization of best lifestyle modifications and guidance to promote a healthy weight, possible medical therapy using FDA-approved weight loss medications and EBMTs with or without concomitant medical therapy.

The purpose of this study is to prospectively evaluate the safety and effectivenes of standard of care, individualized, comprehensive weight loss interventions in carefully selected patients with obesity undergoing cardiac transplant evaluation, including utilization of best lifestyle modifications and guidance to promote a healthy weight, possible medical therapy using FDA-approved weight loss medications and EBMTs with or without concomitant medical therapy.

The purpose of this study is to assess feasibility of measuring gastric physiologic parameters with dynamic MR imaging pre and postoperatively (3 months) in patients undergoing ESG as primary treatment of obesity

The purpose of this study is to determine the effect of endoscopic cryoablation for lessening the effects of dysphagia on the quality of life (QOL) of patients with unresectable esophageal or gastroesophageal junctional cancer.

The purpose of this pilot study to evaluate the performance of biliary optical coherence tomography probe in the detection of dysplasia among primary sclerosing cholangitis patients undergoing liver transplantation and patients with pancreatic ductal adenocarcinoma undergoing Whipple operation and correlating with pathological diagnosis.