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  • Immunotherapy and Ovarian Function Among Premenopausal Melanoma Survivors (ICI OC) Rochester, Minn.

    The purposes of this study are to analyze the ovarian function of female premenopausal melanoma survivors who have undergone immunotherapy, and compare with data from age-matched controls, prospectively investigate ovarian function in premenopausal women with melanoma undergoing immunotherapy, and to identify the impact of ovarian function change on the frequency and function of CD8+ T cells during immunotherapy.

  • Ovarian Tissue Freezing for Fertility Preservation in Girls Facing a Fertility Threatening Medical Diagnosis or Treatment Regimen Rochester, Minn.

    The purpose of this study is to offer ovarian tissue cryopreservation to female pediatric patients (birth-17 years of age) with fertility threatening medical diagnoses or facing surgery, chemotherapy or radiation therapy that may cause loss of reproductive potential. Since this procedure is currently considered experimental, the establishment of an IRB protocol under which this opportunity can be offered is needed.

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