Siva K. Mulpuru, M.D., M.P.H.

Closed for Enrollment

• BradycArdia PaCemaKer With AV Interval Modulation For Blood PrEssure TreAtmenT Rochester, Minn.

  The purpose of this study is to evaluate the safety and effectiveness of a novel atrioventricular interval modulation (AVIM) algorithm downloaded into a previously implanted dual-chamber Medtronic Astra/Azure DR MRI IPG.

• Clinical Evaluation Of The Blazer Open-Irrigated Ablation Catheter For The Treatment Of Paroxysmal Atrial Fibrillation Rochester, Minn.

  The purpose of this study is to establish the safety and effectiveness of the Blazer Open-Irrigated radiofrequency ablation catheter for the treatment of drug refractory, recurrent, symptomatic, paroxysmal atrial fibrillation.

• Concomitant Renal Denervation Therapy in Hypertensive Patients Undergoing Atrial Fibrillation Ablation - A Feasibility Study Rochester, Minn.

  We propose a pilot study to assess safety and benefit of renal artery ablation at the time of planned atrial fibrillation ablation.

• Improving Safety of Lead Extraction Procedures by Traction Force Sensing Rochester, Minn.

  The purpose of this first prospective study is to evaluate force vectors during lead extraction procedures. While the patient and the physicians are aware of the procedure assignments (open label), outcome assessors and statisticians are blinded to the outcomes. Knowledge from this perspective study may ultimately improve patient care; enhance our academic standing, and improve educational satisfaction of our trainees.

• Subcutaneous ICD Therapy Combined With VT Ablation for the Secondary Prevention of Sudden Cardiac Death Rochester, Minn.

  The purpose of this study is to evaluate the feasibility and safety of a management approach that incorporates VT-ablation and S-ICD implantation in secondary prevention patients. This is a single arm prospective study with 30 patients eligible for implantation of an ICD for the secondary prevention of sudden cardiac death.