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Breast Cancer Risk Assessment in Benign Breast Disease
Jacksonville, Fla.
The purpose of this study is to to bring molecular risk prediction for breast cancer into the clinical arena through: the establishment of a large tissue repository from a retrospective cohort of women with benign breast disease with complete and long-term clinical follow-up to identify those who developed breast cancer (cases) and those who did not (controls); the application of potential biomarkers of risk to this archival tissue set; and, the discovery of new, potentially relevant biomarkers of risk in fresh and frozen specimens of benign breast disease.
Closed for Enrollment
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Benign Breast Tissue Studies
Jacksonville, Fla.,
Rochester, Minn.
This study is being done to study what regulates breast tissue growth, to better understand if there is a possible relationship between benign changes and breast cancer. Laboratory studies will search for changes in genetic material (DNA
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Breast Education through Simulation Training (BEST): Post-Mastectomy Wound and Drain Care Patient Education (BEST)
Rochester, Minn.
Plan to conduct a pilot randomized controlled trial to determine the feasibility, benefits and educational impact of using simulation for patient education (SimEd) for post-mastectomy wound and drain care, compared to current patient education practice (StdEd). This study also seeks to derive and validate a skills assessment tool specifically developed to evaluate skills acquired during the education process and compare the results of SimEd vs StdEd; we also plan to relate the scores of our assessment tool to a validated instrument that measures readiness for patient dismissal and compare their results in both study arms.
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