Closed for Enrollment

• A New Dimension in Modeling Irritable Bowel Syndrome (IBS) to Elucidate Novel Diagnostic Biomarkers and Microbiome Signatures Scottsdale/Phoenix, Ariz.

  Microbiota from fecal samples from IBS-D patients, in combination with vitamin D supplementation added to our 3-D immunocompetent intestinal models will establish a high fidelity disease model to achieve our long-term goal to understand the relationship between gut microbiome, vitamin D levels, host gene expression and IBS-D symptoms that could ultimately be used as a testing platform for treatment and prevention.

• A Prospective, Single Arm, Multicenter, Observational Assessment of the Long Term Safety and Efficacy of Solesta® Injectable Bulking Agent for the Treatment of Fecal Incontinence (SoFI) (SoFI) Scottsdale/Phoenix, Ariz.

  The purpose of this observational study is to evaluate the safety and effectiveness of the Solesta Injectable Bulking Agent in the treatment of fecal incontinence through 3 years in a real world setting.

• Proof of Concept: A Commode Assist Device for Excessive Perineal Descent Scottsdale/Phoenix, Ariz.

  Supporting the pelvic floor can reduce symptoms of constipation in patients with refractory constipation due to pelvic floor laxity and excessive perineal descent by means of a modified toilet seat, known as "the Bottom's Up".

• Using Wearable Technology to Increase Daily Activity: A Weight and Wellness Program Initiative Scottsdale/Phoenix, Ariz.

  The purpose of this project is to complete a chart review/ secondary data analysis during the first 6-month program period utilizing data from the 4291 PARTENHEIMER Obesity Registry and interval participant data from the Mayo360 Personalized Support System (Mayo360PSP) questionnaire to examine motivation and behavioral changes in program participants.

   

• Virtual Reality and Obesity: Adolescents Retrain their Brain to Make Healthier Choices Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz.

  The purpose of this study is to:

  1. To test the feasibility of a virtual reality module (VRM) in adolescents (ages 12-18 years) with obesity
  2. To examine the effect of a weight management intervention utilizing the virtual reality module (VRM) on behavior related to nutrition and physical activity as well as body image in adolescents with obesity
  3. To examine the effect of a weight management intervention utilizing the virtual reality module (VRM) on body weight, BMI and waist circumference outcomes in adolescents with obesity
  4. Data from this pilot study will be used as the basis for future funding applications
• Weight and Wellness Solutions Registry Study Scottsdale/Phoenix, Ariz.

  The purpose of this study is to establish a registry database of patients that will be utilized for future research studies related to obesity, health, and weight management strategies.