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  • Biospecimen Resource for Familial Pancreas Research, a Data and Tissue Registry (Also Known as a Bio-repository, Bio-bank, Data and Tissue Database, Data and Tissue Bank, Etc.) to Help Advance Research in Familial Pancreas Disease Rochester, Minn.

    RATIONALE: Collecting and storing samples of blood and tissue from family members of patients with cancer to test in the laboratory may help the study of cancer in the future. PURPOSE: This clinical trial is collecting blood and tissue samples from family members of patients with pancreatic disease, pancreatic cancer, and melanoma.

  • Biospecimen Resource for Pancreas Research (Substudy # 1 - Pancreatic Disease Patients) Scottsdale/Phoenix, Ariz., Jacksonville, Fla., Rochester, Minn.

    RATIONALE: Gathering medical information and collecting and storing samples of blood and tissue to test in the laboratory may help doctors develop better ways to screen people at risk for pancreatic cancer or other pancreatic disorders in the future.

    PURPOSE: This clinical trial is collecting medical information and tissue samples from patients with pancreatic cancer or other pancreatic disorders.

  • Two Cancers, One Gene (TCOG) Rochester, Minn.

    The overall purpose of this study is to understand the factors that increase susceptibility and expression of pancreatic cancer and melanoma in high risk families.  Individuals who are affected with pancreas cancer and melanoma, as well as those without either cancer who have been identified as 1st or 2nd degree relatives of family members with pancreas cancer and melanoma, will be asked to participate. The participant will be asked to complete a survey about their health and family history of cancer and to give a blood sample for specific gene testing and storage for future research studies.

Closed for Enrollment

  • Disclosing Genomic Incidental Findings in a Cancer Biobank: An ELSI Experiment (UNIFY) Rochester, Minn.

    Currently, there is no clear legal or ethical guidance about how researchers and IRBs ought to proceed when the research participant in a biobank is deceased and there is clinically relevant information that could be disclosed to family members. This study is designed to test a procedure offering genetic information to family members of research participants who participated in a pancreatic cancer biobank in a Health Insurance Portability and Accountability Act (HIPAA) -compliant design.

  • Identifying Gene Modifiers of Melanoma and Pancreatic Cancer Susceptibility Rochester, Minn.

    The purpose of this study is to understand the interplay of factors increasing susceptibility and expression of pancreatic cancer and melanoma to develop new diagnostic and chemopreventive regimens.

  • Learning About Research Gene Outcomes (LARGO) (LARGO) Rochester, Minn.

    The purpose of this study is to understand the immediate and delayed feelings, plans, and behaviors of individuals after receiving the results of genetic research testing.

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