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Clinical Studies

Closed for Enrollment

  • Analysis of Patients with Polyuria as a Manifestation of Paroxysmal Atrial Tachyarrhythmias (ATACHPOLY) Rochester, Minn.

    The objective of this study is to investigate this phenomenon by identifying such patients and analyze this relationship using biomarkers (blood and urine signal proteins) related to volume control such as pro-atrial natriuretic peptide (pro-ANP), N-terminal B-type natriuretic peptide (NT-proBNP), cyclic-GMP (a downstream second messenger for natriuretic peptides) and copeptin (the pre-pro-hormone of antidiuretic hormone).

  • Changes in Cardiac Troponin in Response to Change in the Mode and Frequency of Dialysis Rochester, Minn.

    The purpose of this study is to look at a population of stable End-stage renal disease (ESRD) patients receiving conventional hemodialysis (HD) or peritoneal dialysis, to evaluate the association of elevations in cTnT to: a) Levels of selected biomarkers: N-terminal pro-B-type natriuretic peptide (NT-proBNP), high sensitive C Reactive Protein (hsCRP), Asymmetric Dimethyl Arginine (ADMA); b) Clinical parameters – hypertension, hypotension on HD, left ventricular hypertrophy; c) Biochemical parameters – dyslipidemia, hyperphosphatemia, hyperparathyroidism, erythropoietin resistance.