Closed for Enrollment

• An adaptive open label, multiple ascending dose study of the safety, tolerability and bio-effect of Aurase for wound debridement in patients with venous leg ulcers and diabetic foot ulcers. (SC-VLU-001) Jacksonville, Fla.

  To assess the safety and tolerability of multiple ascending doses of Aurase Wound Gel when administered cutaneously (topically) to participants with Venous Leg Ulcers (VLU) ● To assess if the safety and tolerability of the Aurase Wound Gel is similar in DFU participants to what is experienced in VLU participants

   

   

• Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) (CREST) Jacksonville, Fla.

  The purpose of this study is to compare the relatively new procedure of stent-assisted carotid angioplasty to the traditional and accepted surgical approach of carotid endarterectomy for the treatment of carotid artery stenosis to prevent recurrent strokes in those patients who have had a TIA (transient ischemic attack) or a mild stroke within the past 6 months (symptomatic) and in those patients who have not had any symptoms within the past 6 months (asymptomatic).

• Clinical Assessment of the Next Science Wound Gel Efficacy in Chronic Wound Compared to Standard of Care Jacksonville, Fla.

  This is a 3 to 4 months, single site, prospective randomized clinical study of patients diagnosed with a chronic wound. The primary objective is to assess changes in healing rate, by measuring differences in wound area when treating chronic wounds with the Next Science Wound Gel compared to the Triple Antibiotic Ointment Neosporin (Standard of Care, SOC).

• Improving Outcomes of Patients Undergoing Surgical Intervention by Pre-operative Assessment of Nutritional Status, Thyroid Function, and Pathogens Colonization Jacksonville, Fla.

  The aims of this study are:

  1. Assess preoperative nutrition status, thyroid function and pathogen colonization
  2. Correlate these assessments with clinical outcomes
  3. Improve patients satisfaction
• Zinc Versus Multivitamin Micronutrient Supplementation to Support Immune Health in the Setting of COVID-19 Pandemic: A randomized study (Zn COVID Study) Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz.

  The purpose of this study is compare high dose (69.6 mg/day) Zinc to multivitamin supplementation on immune health as used by primary health care staff and individuals over 50 years old identified, by hypothesis generated from observations among the pandemic to date, as being at risk populations to COVID-19. In order to ensure consistent nutritional supplementation, the PreserVision AREDS formulation gel tabs will be recommended for those randomized to Zinc and the Adult (under 50) Centrum formulation recommended for those randomized to multivitamin.