Closed for Enrollment

• A Phase IB Randomized, Placebo-controlled, Double-blinded Study Evaluating the Safety of Ataciguat (HMR1766) in Patients with Moderate Calcific Aortic Valve Stenosis Rochester, Minn.

  This study will determine whether Ataciguat (HMR1766) is well-tolerated in patients with mild to moderate calcific aortic valve stenosis. The primary focus of these studies will be on changes in blood pressure and orthostatic tolerance (i.e., ability to stand up without passing out), and determining whether treatment with Ataciguat results in significant reductions in blood pressure in this patient population.

• Cardiovascular Surgery Biobank Rochester, Minn.

  Researchers in the Division of Cardiovascular Surgery at Mayo Clinic are developing a new research resource called the "Cardiovascular Surgery Biobank" (hereafter referred to as the "Biobank". Participants in the Biobank allow investigators at the Mayo Clinic to obtain diseased tissue that is removed during cardiovascular surgery, and allow access to medical records for research now and in the future. The Biobank serves as a resource for researchers in cardiovascular disease; instead of having to wait for months or years for tissue to be accumulated, researchers can use samples from the Biobank that were normally removed as a part of your surgical procedure.

• Generation of Algorithms for Early Prediction of Aggressive Progression and Hospitalization in Patients Diagnosed with SARS-CoV-2/COVID-19 Infection Rochester, Minn.

  The purpose of this study is to observe participants who have tested positive for COVID-19 using Current Health AI to learn about the disease.

• Generation of Algorithms that Enable Early Detection of Symptomatic SARS-CoV-2/COVID-19 Infection in High Risk Employees Rochester, Minn.

  The purpose of this study is to develop algorithms that will enable earlier identification and testing triggers for COVID-19 in otherwise asymptomatic patients, and to identify baseline characteristics from patients that ultimately test positive for COVID-19 that may predict clinical trajectory during the evolution of disease.

   

• ROR2002: Generation of Algorithms that Enable Early Detection of SARS-CoV-2/COVID-19 Infection and Unrelated Mechanisms of Clinical Decline in High Risk Radiation Oncology Patient Populations (ROR2002) Rochester, Minn.

  The purpose of this study is to develop algorithms that will enable earlier identification and testing triggers for COVID-19 in otherwise asymptomatic patients, and to identify baseline characteristics from patients who ultimately test positive for COVID-19 that may predict clinical trajectory during the evolution of disease.

   

• The Use of Virtual Reality Modules to Reduce Pre-Operative Anxiety in a Cardiac Surgery Inpatient Population Rochester, Minn.

  The purpose of this study is to use Virtual Reality(VR) goggles by inpatients during their pre-operative stay for up to 20 minutes to see if this will decrease objective anxiety measures and improve overall patient satisfaction. 

• The Use of Virtual Reality Modules to Reduce Pre-Operative Anxiety in First Time Sternotomy Patients Rochester, Minn.

  The purpose of this study is to assess the use of low-cost virtual reality equipment and game software to distract and decrease patient reported levels of anxiety while waiting for heart surgery.

• Use of Remote Monitoring to Improve Physician Monitoring, Patient Satisfaction, and Predict Readmissions Following Cardiac Surgery Rochester, Minn.

  The overall goal of this study is to determine whether remote monitoring increases physician monitoring capability, patient satisfaction, and can provide information regarding risk for readmission.