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  • A Pilot Study to Evaluate the Efficacy of Daily Vitamin D3 Supplementation in Normal Weight Adolescents Rochester, Minn.

    The purpose of this study is to measure the blood level of vitamin D in normal weight adolescents following a 12-week supplementation with Vitamin D3 2000 IU/day.

  • A Study of Cardiovascular Risk Factors in Transgender Children and Youth Rochester, Minn.

    The purpose of this study is:

    • Specific Aim 1:  To determine the prevalence of obesity, cardiometabolic risk factors and mental health diagnoses among transgender children and adolescents evaluated at the Mayo clinic Transgender and Intersex Specialty Care Clinic (TISCC)
    • Specific Aim 2:  To measure adipokines related to energy homeostasis and insulin sensitivity in transgender children and adolescents and compare with those in cisgender age and gender matched controls.


  • Development of a Youth Healthy Living Program at the Rochester Alternative Learning Center Rochester, Minn.

    Approximately one third of the children and adolescents in the United States are either overweight or obese. Childhood obesity disproportionately affects specific racial and ethnic groups and households with low socioeconomic status and low parental education. The Alternative Learning Center (ALC) within Rochester School District 535 provides viable educational options for students who are experiencing difficulty in regular educational systems. A greater proportion of students at ALC are minorities, qualify for free and reduced lunch and receive special education services. These children are likely to have unique barriers to physical activity and healthy eating.

    Specific Aims:

    Aim 1: Examine the association between BMI and ethnic/ socioeconomic variables and behaviors related to physical activity and eating in ALC students.

    Aim 2: Develop an age and culturally appropriate on-site program that promotes healthy lifestyle.

  • Effect of Vitamin D Supplementation on Endothelial Function in Obese Adolescents Rochester, Minn.

    Vitamin D deficiency has been linked to endothelial dysfunction in adults. Obese adolescents have a high prevalence of Vitamin D deficiency as well as evidence of endothelial dysfunction. Our hypothesis is that supplementation of Vitamin D deficient adolescents with Vitamin D would lead to improvement in endothelial dysfunction.

  • Prevalence of Vitamin D Deficiency and Cardiometabolic Risk Markers in African American, Hispanic and Somali Adolescents in Olmsted County Rochester, Minn.

    The purpose of this study is to find how many adolescents from the local minority communities have high blood sugar and low vitamin D levels

  • Virtual Reality and Obesity: Adolescents Retrain their Brain to Make Healthier Choices Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz.

    The purpose of this study is to:

    1. To test the feasibility of a virtual reality module (VRM) in adolescents (ages 12-18 years) with obesity
    2. To examine the effect of a weight management intervention utilizing the virtual reality module (VRM) on behavior related to nutrition and physical activity as well as body image in adolescents with obesity
    3. To examine the effect of a weight management intervention utilizing the virtual reality module (VRM) on body weight, BMI and waist circumference outcomes in adolescents with obesity
    4. Data from this pilot study will be used as the basis for future funding applications