David W. Larson, M.D., M.B.A.

This study will assess the ability of the Pathos platform to predict which patients will respond to certain colorectal cancer drug treatments. To demonstrate that for patients with advanced colorectal cancer, prediction scores based on in vitro tumor organoid drug response are positively associated with the rate of first line response.    

To demonstrate that for patients with advanced colorectal cancer, prediction scores based on in vitro tumor organoid drug response are positively associated with progression free survival.

To demonstrate that for patients with advanced colorectal cancer who meet the endpoint of first line response, prediction scores based on in vitro tumor organoid drug response are positively associated with duration of first line response.

The purpose of this study is to establish preliminary evidence of the effiectiveness, safety, and tolerability of LB1148 for the treatment of post-operative ileus and intra-abdominal adhesions in subjects undergoing elective bowel resection.

The Cohera Sylys® Surgical Sealant study is a prospective, randomized, controlled, multicenter technical feasibility clinical study comparing standard anastomosis closure technique (Control) to standard closure techniques plus Sylys® Surgical Sealant (Test) during colorectal and ileorectal anastomosis procedures.

The purpose of this study is to confirm the safety and performance of the da Vinci SP Surgical System, Instruments and Accessories in a complex colorectal procedure such as low anterior resections.

The goal of the study is to assess the correlation of Leo Technology hydration algorithm to various physiological parameters in the perioperative period for those undergoing colorectal surgery.