Martin G. Rodriguez-Porcel, M.D.

Closed for Enrollment

• Implementation of Phase Analysis Cardiac Stress SPECT MPI to Detect Changes in Synchrony Patterns Associated with Ischemia: A Prospective Trial at a Tertiary Referral Center Rochester, Minn.

  The purpose of this study is to determine if MPI SPECT phase analysis can detect varying degrees of abnormal heart rhythm between patients with normal coronary artery circulation, ischemia (poor blood circulation), and infarct (area of dead tissue) from loss of circulation.

• Positron Emission Tomography for the Detection of Subclinical Immune Checkpoint Inhibitor-Induced Myocarditis (PET-SIM): A Prospective, Single Center, Single Arm, Open Label Pilot Study Rochester, Minn.

  The purpose of this study is to evaluate FDG-PET as an imaging modality to diagnose and risk stratify subclinical, imaging negative ICI-myocarditis, and to determine whether subclinical ICI-induced myocarditis is a distinct and clinically relevant entity with a risk of progression to fulminant myocarditis.

• Risk Factors for Mortality in Patients with Severe Left Ventricular Systolic Dysfunction Undergoing Coronary Artery Bypass Grafting Rochester, Minn.

  The purpose of this study is to determine the risk factors for death in patients with severe left ventricular systolic dysfunction undergoing a coronary artery bypass grafting at Mayo Clinic.

• Study of Vascular Dysfunction in Polycystic Kidney Disease (PKD) Rochester, Minn.

  The purpose of this study is to test the hypothesis that patients with PKD have abnormal endothelial function and increased oxidative stress from early stages (eGFR > 60 mL/min/m2, BP<130/90 mmHg), and these correlate with defects in isolated endothelial cells.