Faculty

Scott H. Kaufmann, M.D., Ph.D.

Clinical Studies

Biospecimens For Research On PARP Inhibitor-Associated Myeloid Neoplasms Rochester, MN
The purpose of this study is to assess ex vivo sensitivity of TMNs arising during PARP inhibitor therapy to selected therapeutic agents, including decitabine, venetoclax, A1331852, S63845, prexasertib, adavosertib, ceralasertib, eprenetapopt, pevonedistat, magrolimab, and sabatolimab, both as single agents and in combination.

Changes in the Immune Response to Ovarian Cancer During Chemotherapy Rochester, MN The study will determine whether the type and number of immune cells (white blood cells) in ovarian cancer tumors after initial chemotherapy impacts ovarian cancer patient outcomes.
DOD and SPORE Ovarian Cancer Omics Consortium Analysis of Fallopian Tube Serous Tubal In Situ Carcinoma (STIC) Lesions Jacksonville, FL Rochester, MN
The purpose of this study is to examine the biology of Serous Tubal In Situ Carcinoma (STIC) lesions by conducting a proteomic and genomic analysis of STIC lesions. Fallopian tube serous tubal in situ carcinoma (STIC) lesions are thought to be precursors of fallopian tube and ovarian cancer.