Faculty

Bernard R. Bendok, M.D.

Clinical Studies

Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study (CHESS) Scottsdale/Phoenix, AZ
The purpose of study is to test in moderately symptomatic chronic subdural hematoma (CSDH) patients if middle meningeal artery embolization (MMAE) can be used as an alternative to conventional open surgery.
Patient-Specific Preclinical Evaluation Of Robotic-Assisted Neuroendovascular Access To Support An In-Human Early Feasibility Trial Scottsdale/Phoenix, AZ
The purpose of this study is to characterize the performance of manual MMA access in humans per standard of care.

Minimally Invasive Neuroendoscopic Ultra-Early Targeted ICH Evacuation (MINUTE) Trial Scottsdale/Phoenix, AZ MINUTE is a prospective, multi-center, randomized, controlled, blinded assessor, adaptive enrichment design, clinical trial. Eligible patients with spontaneous BGH ≥20 mL will be randomized 1:1 to either minimally invasive endoscopic SCUBA evacuation plus standard medical management or standard medical management alone; the time of randomization will be used to classify participants in one of two cohorts: 1) those randomized \<8 hours from onset, and 2) those randomized 8-16 hours from onset. Randomization is targeted to occur within 120 min of arrival to the randomizing center's Emergency Department (ED), and initiation of surgery is targeted to occur within 120 min of randomization. Participants will be followed at 30, 90, 180, and 365 days to assess for adverse events (AEs) and utility-weighted modified Rankin Scale (UW-mRS).

A Phase 3 Multicenter Study Of Gleolan (Aminolevulinic Acid Hydrochloride) To Enhance Visualization Of Tumor In Patients With Newly Diagnosed Or Recurrent Meningiomas Scottsdale/Phoenix, AZ Rochester, MN
The purpose of this study is to investigate the safety, diagnostic performance, and clinical usefulness of the imaging agent Gleolan™ (Aminolevulinic Acid Hydrochloride, ALA HCl, ALA, 5-ALA), an orally administered imaging agent for the real-time detection and visualization of meningiomas during tumor resection surgery. ALA is a prodrug that is metabolized intracellularly to form the fluorescent molecule Protoporphyrin IX (PpIX).
Assessing Patient-Specific Anatomy with Holography/Augmented Reality and 3D Printing in Patient Education Scottsdale/Phoenix, AZ
The purpose of this study is to assess if using holography/ Augmented Reality and 3D-printed models to visualize intracranial diseases and aid in patient education.
Feasibility Study Comparing the Utility of GLOW800 and FL800 Intraoperative ICG-VA Tools for Intracranial Lesions Scottsdale/Phoenix, AZ
The purpose of this study is to comparatively evaluate the use of the GLOW800 visualization tool for ICG-VA versus the standard of care visualization tool FL800.