Closed for Enrollment

• ACCRU-SC-1601, A Phase III, Randomized, Controlled, Double-Blind Study Evaluating the Safety of Two Doses of Apixaban for Secondary Prevention of Cancer Related Venous Thrombosis in Subjects Who Have Completed at Least Six Months of Anticoagulation Therapy Rochester, Minn., Jacksonville, Fla., Eau Claire, Wis., Scottsdale/Phoenix, Ariz.

  This randomized phase III trial studies the best dose of apixaban and how well it works in preventing secondary cancer related blood clots in cancer patients who have completed anticoagulation therapy. Apixaban may stop the clotting of blood by blocking some of the enzymes needed for blood clotting.

• Efficacy and Safety of Vascular Boot Warming Program After Acute DVT±PE for Earlier Resolution of VTE and Prevention of Post Thrombotic Syndrome: A Pilot Study Rochester, Minn.

  The Researchers are studying whether a vascular boot warming program plus standard of care anticoagulation can be a safe and effective method to resolve Deep Vein Thrombosis (DVT) ±Pulmonary Embolism (PE) earlier and prevent development of post-thrombotic syndrome (PTS). Additionally, to learn whether a more detailed imaging of the affected lower extremities will provide a more accurate and reliable method to guide treatment for this condition.