Faculty

Iftikhar J. Kullo, M.D.

Clinical Studies

A Patient Decision Aid for Familial Hypercholesterolemia Rochester, Minn.
The purpose of this study is to assist patients and clinicians in discussing the potential benefits and side effects of treatment of familial hypercholesterolemia (FH) and to develop a decision aid for use in a clinical setting.
Cascade Screening for Awareness and Detection of Familial Hypercholesterolemia (CASCADE-FH) Rochester, Minn.
The CASCADE Familial Hypercholesterolemia Registry will track therapy, clinical outcomes, and patient-reported outcomes over time aiming to increase familial hypercholesterolemia awareness, promote optimal disease management, and improve outcomes.
Familial Hypercholesterolemia Identification REgistry (FHIRE) (FHIRE) Rochester, Minn.
The purpose of this study is to develop a registry of molecularly confirmed Familial Hypercholesterolemia (FH) cases in conjunction with the retrospective FHIRE study (IRB# 18-009654) in order to identify and offer genetic testing to Mayo Clinic patients with suspected FH.

Vascular Diseases Biorepository Rochester, Minn.
The eventual goal of this study is to identify genetic and proteomic markers that may influence susceptibility to vascular diseases including peripheral arterial disease, pulmonary hypertension, carotid artery stenosis, arterial aneurysmal disease, fibromuscular dysplasia, congenital heart disease and other less common diseases that affect the blood vessels.

Cardio-Ankle Vascular Index (CAVI) and Left Ventricular Structure and Function Through Transthoracic Echocardiography (Cardiac Echo) Rochester, Minn.
The purpose of the study is to test whether cardio-ankle vascular index, a measure of arterial stiffness that can be obtained in the office setting, is associated with cardiac function and structure as assessed by echocardiography.
Familial Hypercholesterolemia Retrospective Evaluation for Discovery (FHRED) (FHIRE) Rochester, Minn.
The purpose of this study is to identify individuals who may have a condition called Familial Hypercholesterolemia (FH) by using different datasets and methodologies.
Myocardial Infarction Genes (MI-GENES) Study - Using Genomic Data to Refine Risk Assessment for Heart Attack (MI-GENES) Rochester, Minn.
This study is being done to better understand how genetic information might improve assessment of heart attack risk.
Return of Actionable Variants Empirical (RAVE) Study (RAVE) Rochester, Minn.
The purpose of this study is to conduct a genomic medicine implementation project to establish mechanisms for return of actionable findings from targeted sequencing of ~109 disease-relevant genes and genotyping of select polymorphisms in a large study setting (eMERGE III consortium). A primary focus of the Mayo group will be on two common actionable genetic disorders–familial hyperlipidemia (FH) and familial colorectal cancer (CRC).