Mark Denis P. Davis, M.D.

The purpose of this study is to assess clinical feasibility and patient experience with non-invasive computer-assisted video microscopy (CAM) and diffuse reflectance spectroscopy (DRS) of the superficial dermal vessels using ODI technology. Anatomically map nutritive capacity of the superficial dermal microcirculation at various parts of the body (namely, various locations on the lower extremity [including at several arteriosomes), upper chest, and upper extremity] in healthy volunteers and in patients undergoing standard-of-care non-invasive arterial studies for any clinical indication. Correlate results with other variables, such as patient age, sex, tobacco use/diabetes status, anatomic location of testing, degree of edema, and results of non-invasive arterial studies. Generate hypotheses for specific future scientific inquiry based on preliminary findings from the work completed in aims 1-3.

 

The purpose of this study is to:

1. To determine the response rates and toxicity in patients that have undergone skin directed radiation therapy for inflammatory cutaneous dermatoses.
2. To review and report the institutional experience, clinical responses, and recurrence rates after skin directed radiation therapy by varying dosing regimens and treatment regimens.
3. To gather information on technical innovations used in the treatment of inflammatory dermatoses with the goal of publishing our findings so that others can utilize techniques we have found to be useful in the treatment of particularly challenging cases.