Paul A. Friedman, M.D.

A study to evaluate feasibility, diagnostic yield, accuracy, and actionable thresholds of POC, immediate-feedback AI-ECG + AI FoCUS screening for cardiac disease in well described community populations.

Prospective, single-arm, non-randomized, unblinded, chronic feasibility study designed to evaluate the safety and performance of the AVEIR™ Conduction System Pacing (CSP) Leadless Pacemaker system.

The ALARION EV Study is a prospective, multi-center, single-arm, non-randomized study without concurrent or historical controls. The purpose of this pivotal study is to generate evidence of safety and effectiveness to apply for regulatory approvals for commercialization of the Parasternal EV-ICD System.

The objective of the study is to demonstrate safety and effectiveness of the Parasternal EV-ICD System through 6-months.

The purpose of this study is to evaluate the safety and effectiveness of the AveirTM Dual-Chamber (DR) Leadless Pacemaker (LP) system in patients indicated for a DDD(R) pacemaker to support regulatory approval for the Aveir DR LP system for DDD(R) pacing indications and the Aveir atrial LP for AAI(R) pacing indications.

The purpose of this study is to determine whether a wristband that detects your pulse can detect your heart rate and rhythm similar to electrocardiograms (ECG).

The purpose of this study is to modify and adapt the algorithm to be usable in a mobile form factor with a limited number of leads. For this, will prospectively test and validate the adapted algorithm in outpatients presenting to the echocardiography laboratory and to test the sensitivity and specificity of a single lead ECG to identify people with decreased left ventricular EF.

The purpose of this study is to determine the accuracy of a non-invasive approach to estimate potassium levels using surface ECG's from patients undergoing hemodialysis.

The purpose of this study is to gather information to understand the effect of body position on ECGs using artificial intelligence.

The purpose of this study is to assess cardiovascular health and detect unknown and asymptomatic diseases using Mayo AI-ECG algorithms.

We hypothesize that using single lead ECGs and symptoms data collected by patients using their personal Apple Watch (FDA approved for AF detection) via a Mayo Clinic app, will allow data to be shared within a dashboard in Epic, so physicians may have a way to remotely assess cardiovascular health.

The primary purpose of this study is to explore KardiaK performance in a controlled and comprehensive clinical setting, including collection of relevant data such as patient medical history, and medications affecting potassium.  In addition, it is intended to explore KardiaK performance when serial ECGs are recorded and to explore KardiaK performance using a 12-lead ECG and two novel ECG recording devices designed for home use.

The purpose of this study is to assess the serum potassium and cardiac rhythm trends in subjects with end stage renal disease (ESRD) who are on 3 times weekly maintenance hemodialysis for at least 60 days.

The purpose of this study is to observe the remote ECG signals of Nanostim pacemaker patients utilizing the AliveCor device, and compare these ECG signals with ECG recordings collected with the Nanostim device programmer during their clinical follow-up.

Prospective, non-randomized, multi-center, international clinical study is designed to confirm the safety and effectiveness of the Aveir LP System in a subject population indicated for a VVI(R) pacemaker.

An important means to control the COVID-19 pandemic is the rapid identification of infected individuals to allow quarantine and therapy to be promptly delivered.  At home testing will soon be available, but requires reagents and introduces a delay.  The possibility of combining a limited number of Mid-Turbinate (MT) nasal swab tests, Dried Blood Spot (DBS) serology, and smartphone-enabled electrocardiogram (ECG) tests may permit daily rapid, under one minute tests potentially, if this method proves to be effective. We plan to enroll 900 participants to determine if we can detect conversion in all modalities.

This is a prospective, non-randomized, multicenter, pivotal Investigational Device Exemption (IDE) study. The intent of this study is to demonstrate the safety and effectiveness of the ST Monitoring Feature in St Jude Medical ICD systems.