Closed for Enrollment

• CPN1742 Differential Gene Expression Signature as a Predictive Biomarker of an Immune Response to a Preventative Cancer Vaccine Rochester, Minn. Can the genetic makeup of an individual who does not yet have cancer provide an indication of the risk of future cancer?
• CPN1942 The GUCY2C-cyclic GMP Pharmacodynamic Axis in Organoids from Rectal Mucosa Rochester, Minn.

  The purpose of this study is to explore the level of similarity in pharmacodynamic responses to GUCY2C agonists in organoids prepared from rectal biopsies from all healthy subjects, independent of changes in their bowel movements induced by oral administration of 27 mg/day of dolcanatide for 7 days.