Faculty

Timothy I. Morgenthaler, M.D.

Clinical Studies

An App-Based, Precision Medicine Approach to Optimize Long-Term CPAP Adherence and Quality of Life Rochester, Minn., Scottsdale/Phoenix, Ariz.
The purpose of this study is to conduct two optimization trials that test decision rules and adaptive algorithms programmed into the smartphone application SleepWell24 to optimize for early CPAP adoption to achieve > 6 hours/night for ≥ 6 nights/week of CPAP; and to optimize long-term health-related QoL and long-term CPAP maintenance over 6 months.
Diversity in Residential Environment and Assessment in Sleep Medicine (DREAM Study) Rochester, Minn.
This study aims to explore the diversity of sleep environments among patients at the Center for Sleep Medicine and understand the factors influencing their choices. The survey will be limited to new consultations across Mayo Clinic’s Centers for Sleep Medicine in Rochester, Florida, Arizona, and Mayo Clinic Health System locations to capture variability in sleep environments across different geographic and demographic patient populations. By addressing variability in sleep environments, this study seeks to improve diagnostic accuracy and treatment decisions, especially with the increasing reliance on home sleep testing.

Evaluating an Under-mattress Sleep Monitor Compared to a Peripheral Arterial Tonometry Home Sleep Apnea Test Device in the Diagnosis of Obstructive Sleep Apnea Rochester, Minn.
The purpose of this study is to eEvaluate an under-mattress sleep monitor compared to a peripheral arterial tonometry home sleep apnea test device in the diagnosis of obstructive sleep apnea.
Evaluation of a Wearable Physiologic Monitor to Detect Sleep Quality Rochester, Minn.
The purpose of this study is to demonstrate proof-of-concept feasibility for Mayo OMNI physiologic monitor correlation with sleep-wake measures obtained from the current gold-standards of actigraphy and polysomnography.
Evaluation of An Optical Measurement Algorithm Combined with Patient and Provider Input to Reduce Mask Exchanges During Initial Positive Airway Pressure Therapy Rochester, Minn.
The purpose of this study is to evaluate whether use of the app to recommend positive airway pressure (PAP) masks reduces patient-initiated request for mask changes during the first 90 days of PAP use., and to evaluate whether use of the app results in improved patient satisfaction with PAP experience during the first 90 days of PAP use.
Prospective Non-randomized Post Market Study Collecting Clinical Data on Safety and Effectiveness of the remedē® System (rēST) Rochester, Minn. The purpose of this non-randomized post market study is to collect clinical data on the safety and effectiveness of the remedē System in a real-world setting.