Closed for Enrollment

• A Phase 2 Open-label Multi-centre Study to Evaluate the Efficacy and Safety of Oxabact ® to Reduce Plasma Oxalate in Subjects With Primary Hyperoxaluria Who Are on Dialysis Rochester, Minn.

  The purpose of this study is to determine if Oxalobacter formigenes is effective at lowering plasma oxalate levels in patients with primary hyperoxaluria who are on dialysis.

• Correlation of Disease Expression With Specific Genetic Mutations in Primary Hyperoxaluria Rochester, Minn.

  This study will help us determine whether certain genetic mutations, more than others, are a cause of more severe disease in Primary Hyperoxaluria.

• Potential Metabolism of Polyethylene Glycol to Oxalate Rochester, Minn.

  The purpose of this research study is to determine if the frequent use of polyethylene glycol (MiraLAX) may cause hyperoxaluria - an abnormally high level of oxalate in the urine.