Closed for Enrollment

• A Randomized Study Of Biologic Scaffolds And Esophageal Healing Following Endoscopic Resection Rochester, MN

  This study is being done to assess the use of scaffold products in promoting constructive healing as determined by the ability of the resection site to lift during follow-up.

• CryoSpray Ablation for Barrett's Esophagus After Treatment Failure With Serial RadioFrequency Ablation (BEATS-RF) Rochester, MN

  The purpose of this study is to determine whether cryotherapy is effective in the treatment of persistent high grade dysplasia (HGD) or early esophageal adenocarcinoma (IMCA) in patients who have not responded to radiofrequency ablation (RFA).

• Endoscopic Image And Pathology Correlation For Duodenal Biopsy Findings Using Fujifilm 7000 Blue Light Imaging System With 4-LED Multi Light Technology Rochester, MN

  The purpose of this study is to match endoscopic images with standard of care endoscopic biopsies to determine if the images can diagnose as effective as biopsies for duodenal/small bowel biopsies.

• Eradicating Barrett's Esophagus Using Radiofrequency Ablation Or A Novel Hybrid Argon Plasma Coagulation Technique (BURN) Scottsdale/Phoenix, AZ Jacksonville, FL Rochester, MN

  The purpose of this study is to investigate if Hybrid Argon Plasma Coagulation (HAPC) is non-inferior to Radiofrequency Ablation (RFA) in the stricture-free eradication of the dysplastic Barrett's Esophagus (BE) epithelium.

   

• Identification Of Features Associated With Dysplasia Using The NvisionVLE® Imaging System Pilot Trial Rochester, MN

  The purpose of this study is to evaluate the performance of the NvisionVLE® Imaging System for determining features of dysplastic Barrett's Esophagus by collection and analysis of medical record information, imaging data, and pathology results. The study is for patients who have a prior biopsy-confirmed diagnosis of Barrett's esophagus with dysplasia and are scheduled to have an endoscopic evaluation.

• Interscope Endorotor® Mucosal Resection System With Continued Ablative Therapy In Subjects With Refractory Dysplastic Barrett's Esophagus Rochester, MN

  The aim of the clinical trial is evaluate the EndoRotor®’s ability to completely remove areas of Barrett’s metaplasia considered refractory after failed ablative therapy.

   

   

   

• Natural History Of Barrett's Esophagus Using Tethered Capsule Endomicroscopy Jacksonville, FL Rochester, MN

  The goal of this research is to determine the natural history of Barrett's esophagus (BE) using tethered capsule endomicroscopy (TCE) in patients undergoing surveillance endoscopy.

• Notch Signaling And Novel Biomarkers For Barrett’s Esophagus Scottsdale/Phoenix, AZ Jacksonville, FL Rochester, MN

  The purpose of this study is to determine biomarkers which can predict response to ablation therapy in patients with Barretts esophagus.

• Notch Signaling And Novel Biomarkers For Barrett’s Esophagus Scottsdale/Phoenix, AZ Jacksonville, FL Rochester, MN

  The purpose of this study is to determine biomarkers which can predict response to ablation therapy in patients with Barretts esophagus.

• Performance of Clutch Cutter vs. Conventional Endoscopic Submucosal Dissection Methods among Gastroenterology Trainees in an Ex Vivo Model Rochester, MN

  The purpose of this study is to assess for differences between Clutch Cutter vs. conventional endoscopic submucosal dissection techniques with regards to; Time to incision; Time to dissection; Total procedure time; Number of perforations; and Ease of use as determined by participant questionnaire.

• Wide Area Transepithelial Sample Esophageal Biopsy Combined With Computer Assisted 3-dimensional Analysis (WATS) For The Detection Of Esophageal Dysplasia: A Prospective, Randomized, Tandem Study Rochester, MN

  The purpose of this study is to see if collecting cells from the lining of the esophagus with a brush in addition to the biopsies taken for standard medical care will have a better rate of finding cancer cells related to having Barrett's esophagus.