Health and Quality of Life Among Long-Term Lung Cancer Survivors

This study in the Epidemiology and Genetics of Lung Cancer Research Program at Mayo Clinic identifies factors that can affect quality of life for lung cancer survivors.

Through the Health and Quality of Life Among Long-Term Cancer Survivors study, participants with lung cancer are followed for up to 10 years. Data gathered over time enables the research team to create a profile of survivor well-being and to screen for factors that may affect the clinical long-term prognosis and quality of life (QOL) for people with lung cancer.

After identifying factors that affect overall quality of life or specific domain of QOL dimensions, effective interventions are tested, recommended and implemented.

Select related publications

  • Frost MH, Novotny PJ, Johnson ME, Clark MM, Sloan JA, Yang P. Spiritual well-being in lung cancer survivors. Support Care Cancer. 2013;21(7):1939-46. PMID: 23420557; PMCID: PMC3669652.
  • Solberg Nes L, Liu H, Patten CA, Rausch SM, Sloan JA, Garces YI, Cheville AL, Yang P, Clark MM. Physical activity level and quality of life in long term lung cancer survivors. Lung Cancer. 2012;77(3):611-6. PMID: 22681871; PMCID: PMC3882512.
  • Sloan JA, de Andrade M, Decker P, Wampfler J, Oswold C, Clark M, Yang P. Genetic variations and patient-reported quality of life among patients with lung cancer. J Clin Oncol. 2012;30(14):1699-704. PMID: 22454423; PMCID: PMC3383115.
  • Yang P, Cheville AL, Wampfler JA, Garces YI, Jatoi A, Clark MM, Cassivi SD, Midthun DE, Marks RS, Aubry MC, Okuno SH, Williams BA, Nichols FC, Trastek VF, Sugimura H, Sarna L, Allen MS, Deschamps C, Sloan JA. Quality of life and symptom burden among long-term lung cancer survivors. J Thorac Oncol. 2012;7(1):64-70. PMID: 22134070; PMCID: PMC3241852.
  • Cheville AL, Novotny PJ, Sloan JA, Basford JR, Wampfler JA, Garces YI, Jatoi A, Yang P. The value of a symptom cluster of fatigue, dyspnea, and cough in predicting clinical outcomes in lung cancer survivors. J Pain Symptom Manage. 2011;42(2):213-21. PMID: 21398089; PMCID: PMC3382064.
  • Yang P, Mandrekar SJ, Hillman SH, Allen Ziegler KL, Sun Z, Wampfler JA, Cunningham JM, Sloan JA, Adjei AA, Perez E, Jett JR. Evaluation of glutathione metabolic genes on outcomes in advanced non-small cell lung cancer patients after initial treatment with platinum-based chemotherapy: an NCCTG-97-24-51 based study. J Thorac Oncol. 2009;4(4):479-85. PMID: 19347979; PMCID: PMC2998042.
  • Yang P. Epidemiology of lung cancer prognosis: quantity and quality of life. Methods Mol Biol. 2009;471:469-86. PMID: 19109795; PMCID: PMC2941142.
  • Jatoi A, Novotny P, Cassivi S, Clark MM, Midthun D, Patten CA, Sloan J, Yang P. Does marital status impact survival and quality of life in patients with non-small cell lung cancer? Observations from the Mayo Clinic lung cancer cohort. Oncologist. 2007;12(12):1456-63. PMID: 18165623.
  • Sugimura H, Yang P. Long-term survivorship in lung cancer: a review. Chest. 2006;129(4):1088-97. PMID: 16608961.
  • Jatoi A, Williams B, Nichols F, Marks R, Aubry MC, Wampfler J, Finke EE, Yang P. Is voluntary vitamin and mineral supplementation associated with better outcome in non-small cell lung cancer patients? Results from the Mayo Clinic lung cancer cohort. Lung Cancer. 2005;49(1):77-84. PMID: 15949593.
  • Jatoi A, Williams BA, Marks R, Nichols FC, Aubry MC, Wampfler J, Yang P. Exploring vitamin and mineral supplementation and purported clinical effects in patients with small cell lung cancer: results from the Mayo Clinic lung cancer cohort. Nutr Cancer. 2005;51(1):7-12. PMID: 15749624.
  • Garces YI, Yang P, Parkinson J, Zhao X, Wampfler JA, Ebbert JO, Sloan JA. The relationship between cigarette smoking and quality of life after lung cancer diagnosis. Chest. 2004;126(6):1733-41. PMID: 15596667.