Collaboration

Advancing biotherapeutics through industry, academic and enterprise partnerships

The Center for Regenerative Biotherapeutics at Mayo Clinic is dedicated to transforming patient care through the development and deployment of cutting-edge regenerative therapies. We bring together expertise from industry, academia and enterprise groups to accelerate innovation and deliver hope to patients facing some of medicine's greatest challenges. Our mission is to bridge scientific discovery with clinical application, expanding access to novel biotherapeutics and advancing the science of regenerative medicine.

Industry collaboration

We partner with companies that seek to license biotherapeutics developed at Mayo Clinic. We offer robust clinical and manufacturing expertise to facilitate the clinical translation of new therapies. Our internal biomanufacturing capabilities enable us to codevelop products with biotech companies that possess promising early-stage technologies. Collaborators benefit from our experience in:

  • Biomanufacturing quality.
  • Clinical development.
  • Clinical trials.
  • Process and analytical development.
  • Regulatory affairs.

We help overcome barriers related to cost and knowledge of Current Good Manufacturing Practice regulations, bringing potential cures to patients faster.

We welcome partnerships with companies possessing or enabling technologies of interest. Our team provides comprehensive support in process optimization, quality assurance and regulatory compliance, ensuring that promising biotherapeutics advance smoothly from discovery to clinical application.

Academic partnerships

We collaborate closely with academic researchers in fields such as:

  • 3D bioprinting.
  • Biomaterials.
  • Cellular and gene therapy.
  • Tissue engineering.

These partnerships enable the translation of innovative discoveries into therapies for first-in-human clinical trials. By combining technical knowledge with clinical expertise and advanced manufacturing capabilities, we deliver truly novel treatments and cures to patients in need.

Multi-institution grants and contracts

We engage in joint projects with companies and academic institutions through large multi-institution grants and contracts in biotherapeutics. These collaborative efforts drive progress in regenerative medicine and foster new opportunities for technology commercialization and clinical development.

Mayo Clinic collaborations

The Center for Regenerative Biotherapeutics advances the work of field-leading biomanufacturing research groups and initiatives across the enterprise.

Mayo Clinic Comprehensive Cancer Center

We collaborate closely with Mayo Clinic Comprehensive Cancer Center on innovative targets for chimeric antigen receptor (CAR)-T cell therapy in cancer treatment, advancing unique approaches for patients with hard-to-treat malignancies.

RNA Therapeutics Discovery and Translation Program

We work with the RNA Therapeutics Discovery and Translation Program recharge facility in Jacksonville, Florida, to advance initiatives in antisense oligonucleotides (ASOs), lipid nanoparticles (LNPs) and messenger RNA (mRNA) technologies. This collaboration accelerates the development and delivery of advanced RNA-based therapies.

Transforming Transplant initiative

The center supports enterprise initiatives such as Mayo Clinic Transforming Transplant, which includes a close collaboration with Carnegie Mellon University. Together, we are reimagining transplantation science and advancing new approaches to patient care.

Regenerative Medicine Minnesota

Mayo Clinic is a key partner in Regenerative Medicine Minnesota, a statewide initiative to advance regenerative medicine and position Minnesota as a leader in the field. The program aims to improve health outcomes and create economic opportunities through technology commercialization. The Minnesota Legislature has provided ongoing funding to support research, biobusiness development and outreach education. Mayo Clinic researchers have received grants to drive innovation, expand biobusiness and promote regenerative medicine across the state.

Learn more on the Regenerative Medicine Minnesota website.