Joline E. Brandenburg, M.D.

Joline E. Brandenburg, M.D., of Mayo Clinic in Rochester, Minn., hopes cutting-edge translational research will better answer questions and improve upon current treatments for children with disabilities.

"I'm frequently faced with questions from families about the effects of treatment interventions on their children and into adulthood, as well as their prognosis for walking and physical function," says Dr. Brandenburg, who specializes in pediatric rehabilitation, a growing subspecialty of physical medicine and rehabilitation.

Dr. Brandenburg is quantifying muscle stiffness in young children with spasticity from cerebral palsy and the effect of botulinum neurotoxin on the muscle. Today, there is not a routine, clinically applicable way to measure the effect of botulinum neurotoxin on muscle stiffness in children without inducing spasticity.

Dr. Brandenburg is using a new technology, shearwave dispersion ultrasound vibrometry, which allows her to do a noninvasive ultrasound. It can be used with B-mode ultrasound technology to provide rapid, repeated measurements of muscle stiffness and is independent of inducing spasticity in children.

Dr. Brandenburg says Mayo Clinic embodies a multidisciplinary, collaborative approach to research and clinical practice.

"Mayo has an incredible reputation of world-renowned researchers. I have the opportunity to learn, work and collaborate with three major research labs. They have come together with great enthusiasm and support. I feel I am in the right place to be supported as I develop my research career," says Dr. Brandenburg.

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  • Dec 11, 2012
  • PRO057100