Carrie B. Hruska, Ph.D.

Carrie B. Hruska, Ph.D., of Mayo Clinic in Rochester, Minn., is interested in developing and improving tools to predict a woman's risk of developing breast cancer. Dr. Hruska says she has access to cutting-edge breast-imaging modalities and image processing tools at Mayo Clinic that are essential for the success of her research.

She is applying her knowledge of medical-imaging technology to understand how the imaging appearance of a woman's normal breast tissue may be used to assess the likelihood that she will develop breast cancer in the future.

"This information would be very useful to the clinician in selecting appropriate screening strategies and guiding clinical management of patients, particularly for women who have breast tissue that appears dense on mammography," says Dr. Hruska.

Dr. Hruska is researching the underlying histologic processes in dense breast tissue that account for a range of different imaging appearances among patients. She collects samples of benign breast tissue from patient volunteers and compares the histologic appearance with its imaging appearance.

"Mayo offers the unique opportunity of working with leading experts in the study of breast density, the understanding of histopathology of benign breast tissue and the clinical management of patients with dense breasts," says Dr. Hruska. "Our plan is to build a large database of imaging studies and tissue samples in order to develop a risk-prediction model for determining an individual woman's density-related risk."

"The KL2 Program is a critical next step in my career. I'm looking forward to the opportunity for in-depth study in epidemiologic methods and research methodology as I aim to transition into an independent clinical researcher in the field of breast imaging and breast cancer risk," says Dr. Hruska.


  • May 3, 2013
  • PRO520344