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Male Recipient Cell
Female Donor Cell
A male patient with a complex abnormal karyotype (left) has received a bone marrrow transplant from a normal female (right). The success of the transplant can be measured by monitoring the presence of male recipient cells versus female donor cells. The goal of a transplant is to eliminate the recipient's bone marrow and replace it with donor cells that eventually repopulate the bone marrow. The presence of recipient cells indicates that the transplant was not completely successful. FISH is also used very effectively to monitor the success of bone marrow transplants.
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