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Cytogenetic Technology Program

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Cytogenetic Technology Overview

Chromosomes

Cancer

Congenital Syndromes

Treatment Regimen

Response to Therapy

Miscarriages

New Therapies

FISH Basics

Gene Level

Microdeletions

Interphase Nuclei

Types of FISH Probes

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Hyperdiploidy in ALL

Hyperdiploid (more than 46 chromosomes) karyotype commonly seen in pediatric acute lymphoblastic leukemia (ALL).   This karyotype has 54 chromosomes with an extra X, 4, 6, 14, 17, 18, 21 and 22.  Patients with this type of karyotype have a more favorable prognosis and can be treated less aggressively with chemotherapy regimens.
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