ROBERT KOCH (1843-1910) was born in Klausthal, Hanover, Germany. He graduated at Gôttingen in 1866, and began his career as a country practitioner. In 1876 he demonstrated to Ferdinand Cohn of Breslau his work on the etiology of anthrax based on the development of the anthrax bacillus. In 1878 he published his important monograph on wound infections. In 1880 he was appointed to a position in the Imperial Health Office where in 1881 he developed a new method of obtaining pure cultures of bacteria by using a meat infusion mixed with warm gelatin, which hardened after being poured upon glass plates. This was a very important advance for bacteriology. In 1882, Koch discovered the tubercle bacillus. He also discovered tuberculin, which was not a cure of tuberculosis but proved to be of great value in diagnosis of the disease.