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Services and Assays


The Metabolomics Core:

  • Develops stable isotope methodologies and makes them available to clinical investigators across various disciplines
  • Provides advice and expertise in the application of stable isotope-labeled tracer techniques
  • Offers measurement of metabolic profiles, both in terms of metabolite identification and quantification


Assays available in the core and those under development include:

Mass spectrometry (gases)
CO2Expired air
Doubly labeled waterUrine
Gas chromatography mass spectrometry (GC/MS)
[6,6-d2]glucose plus [1-13C]glucose panelPlasma
Liquid chromatography with tandem mass spectrometry (LC-MS/MS)
[ring-13C6]phenylalanineTissue fluid
[d5]phenylalanineTissue fluid
[d4]cortisol plus cortisone panelPlasma
[4-13C]cortisol plus [d7]cortisone panelPlasma
[ring-13C6]phenylalanineGel spots
[d5]phenylalanineGel spots
Ceramide plus metabolitesPlasma or tissue
Free fatty acid (FFA) panelPlasma
[U-13C]palmitoyl carnitineMuscle
[13C4]palmitoyl carnitineMuscle
[U-13C]oleoyl carnitineMuscle
Large-scale metabolites profilingPlasma or tissue
Diazepam plus metabolites panelMedia
Gas chromatography combustion isotope ratio mass spectrometry (GC-C-IR/MS)
Under development
Metabolites identificationPlasma or tissue
Citric acid fluxTissue
Diacylglycerol (DAG)Plasma or tissue
Glutamic acid fluxPlasma
Arachidonic acid plus metabolitesPlasma or tissue
  • ART202263