PCORI awards over $2 million for Mayo study on mild cognitive impairment
The Patient-Centered Outcomes Research Institute (PCORI) has awarded a contract to Glenn E. Smith, Ph.D., L.P., for a study titled "Comparative Effectiveness of Behavioral Interventions to Prevent or Delay Dementia (CEBIPODD)."
This study will focus on the impact of physical activity, brain fitness, memory compensation training, support groups and wellness education on daily function, cognition, quality of life, mood and self-efficacy in mild cognitive impairment (MCI) patients and caregivers.
"There is research providing supporting evidence for each of these separate interventions but little comparing each component to the others. Thus, we cannot say for sure which components deliver the highest value for patients and their families, nor if any are unnecessary given the presence of the other components," says Dr. Smith.
In the CEBIPODD study, participants will be randomly assigned to engage daily in four of the five above-listed components of the Healthy Action to Benefit Independence and Thinking (HABIT) 10-day brain and body wellness program.
The CEBIPODD study launches in July 2014 with a survey to past program participants to finalize outcome priorities and design issues. CEBIPODD is seeking 364 MCI patients and their program partners across Mayo Clinic when the trial launches in September.
A support partner is required to complete the program with the participant. The program builds on existing strengths and recognizes that procedural memory, otherwise known as "habit," can be exercised to promote the highest level of function and independence.
These sessions are delivered by a caring, multidisciplinary HABIT team that includes psychologists, education specialists, cognitive interventionists and exercise specialists.
The HABIT Program is integrated, coordinated and standardized at all Mayo Clinic campuses — Rochester, Minnesota; Phoenix/Scottsdale, Arizona; and Jacksonville, Florida. Each campus will offer four sessions of the CEBIPODD study of HABIT each year.
The study is one of 82 proposals approved in the last cycle of PCORI funding to advance the field of patient-centered comparative effectiveness research and provide patients with information that will help them make better-informed decisions about their care.
"This project was selected for PCORI funding not only for its scientific merit and commitment to engaging patients and other stakeholders, but also for its potential to fill an important gap in our health knowledge and give people information to help them weigh the effectiveness of their care options," says PCORI Executive Director Joe Selby, M.D., M.P.H. "We look forward to following the study's progress and working with Mayo Clinic to share the results."
For more information, watch the HABIT Program online orientation or call:
- Mayo Clinic, Rochester, Minnesota — 507-284-1324
- Mayo Clinic, Jacksonville, Florida — 904-953-8853
- Mayo Clinic, Phoenix/Scottsdale, Arizona — 480-301-8297