Photograph showing the hands of a researcher working in the lab in the Mayo Clinic Ovarian Cancer SPORE Overcoming the challenges of ovarian cancer

With expertise in basic research, population science and clinical investigation, our team of investigators is targeting new and better ways to prevent, diagnose and treat ovarian cancer.

Overview

The Mayo Clinic Ovarian Cancer SPORE supports and conducts research aimed at improving the diagnosis and treatment of ovarian cancer and related cancers, including fallopian tube cancer and primary peritoneal cancer.

Our investigators are urgently conducting clinical trials and research to advance scientific understanding about ovarian cancer, which often goes undetected until it has spread within the pelvis and abdomen and is more difficult to treat. Investigators for the Ovarian Cancer SPORE focus research efforts on four major translational research projects. Within those projects, they're studying biomarkers, PARP inhibitors, targeted protein kinases, BRCA-mutated advanced ovarian cancer, novel uses for therapeutics such as metformin, and vaccine therapy in the push to overcome unmet patient needs.

Co-investigators in the SPORE's research projects have expertise in basic research, population science and clinical investigation. The SPORE applies an interdisciplinary approach to meet our objectives for research. Our investigators work together as a team to meet the goals of the SPORE and with investigators from SPOREs and ovarian cancer research groups at other institutions in a collaborative effort to improve therapeutic outcomes for patients.

Four cores support all aspects of our research efforts, including leadership, specimens, statistical collaboration and research models:

The SPORE also supports programs that provide research funding and career development to investigators, including both new investigators and seasoned investigators who want to redirect their work to ovarian cancer.

Funding

The Ovarian Cancer SPORE is part of the Women's Cancer Program, a formal research program within Mayo Clinic Cancer Center.

The SPORE is funded by the National Cancer Institute (NCI), which awarded Mayo Clinic a five-year, $11.2 million grant in September 2015. A SPORE, or Specialized Program of Research Excellence, is the cornerstone of the NCI's efforts to promote collaborative, interdisciplinary translational research.

Principal investigator

The principal investigator for the Mayo Clinic Ovarian Cancer SPORE is: