Research

The Hematologic Malignancies Program studies the epidemiology and progression of hematologic malignancies and develops new treatment strategies.

To aid this research, the program is organized into four disease-oriented groups:

  • Chronic lymphocytic leukemia
  • Lymphoma
  • Multiple myeloma and amyloid diseases
  • Myeloid diseases, including myeloproliferative disorders, acute leukemia and myelodysplasia

Program investigators work within and across these four disease groups because studies are often complementary — a better understanding of one disease helps develop better treatment for another. In addition, each researcher brings his or her own unique expertise, whether basic research, clinical research or patient care. The Hematologic Malignancies Program collaborates with numerous Mayo Clinic faculty members on these defined research focus areas.

Chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is a cancer of the blood and bone marrow that most commonly affects older adults.

Faculty members collaborating on CLL research include:

Lymphoma

Lymphoma is a cancer of the lymphatic system, and includes Hodgkin's lymphoma and non-Hodgkin's lymphoma.

Faculty members collaborating on lymphoma research include:

Myeloma and amyloid disease

Multiple myeloma is a cancer of plasma cells, which are a type of white blood cell present in bone marrow. Amyloid disease, also called amyloidosis, is a rare disease that develops when substances called amyloid proteins build up in organs.

Faculty members collaborating on myeloma and amyloid disease include:

Myeloid diseases, including myeloproliferative disorders, acute leukemia and myelodysplasia

Myeloid diseases are cancers that affect white blood cells called myeloid cells. Myeloproliferative disorders (myeloproliferative neoplasms) cause red and white blood cells or platelets to grow abnormally and spread in the bone marrow. Leukemia, including acute leukemia, is a cancer of the blood and bone marrow that causes bone marrow to overproduce a certain type of white blood cell. Myelodysplasia, also called myelodysplastic syndrome, is a group of disorders caused by poorly formed or dysfunctional blood cells.

Faculty members collaborating on myeloid diseases, myeloproliferative disorders, acute leukemia and myelodysplasia include: