Location

Rochester, Minnesota Clinical Profile

Summary

Dr. Sarkaria's laboratory research is focused on developing novel radiosensitizing strategies for the treatment of glioblastoma. Studies in the Sarkaria laboratory demonstrated that concurrent treatment with rapamycin can significantly enhance the efficacy of radiation therapy, and these studies have led to the development of a clinical trial that will evaluate this combination in newly diagnosed patient with GBM. Other studies in the laboratory are focused on understanding the potential benefit of EGFR inhibitors in combination with radiation therapy and evaluating mechanisms of sensitivity and resistance to temozolomide when combined with radiation. Dr. Sarkaria also is interested in imaging drug induced changes in tumor proliferation as a method for rapidly identifying those patients who are benefiting from a particular novel therapeutic strategy.

Recent Publications

See my publications

Professional Details

Primary Appointment

  1. Radiation Oncology

Academic Rank

  1. Professor of Radiation Oncology

Education

  1. Post Doctoral Research Department of Oncology
  2. Research Fellowship - Radiotherapy Research Unit Institute of Cancer Research
  3. Resident - Radiation Oncology University of Wisconsin, Madison
  4. Internship - Transitional University of Hawaii
  5. MD University of California, Los Angeles
  6. BS - Biology and Chemistry University of California, Irvine
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BIO-00027456

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