Location

Jacksonville, Florida

Contact

das.pritam@mayo.edu

Summary

Research in the laboratory of Pritam Das, Ph.D., focuses on the role of inflammation, the brain's innate immune system, and changes with aging in the development and progression of Alzheimer's disease. Specifically, Dr. Das' team is investigating how such inflammatory pathways may impact the development or progression of Alzheimer's disease.

Dr. Das' research team has generated a wealth of data showing that inflammatory markers in the brain could prevent amyloid deposition in the brain using mouse models of Alzheimer's disease. Based on this work, Dr. Das' team hypothesizes that it may be possible to harness these immunomodulatory pathways to potentially slow or prevent progression of Alzheimer's disease.

Focus areas

  • Role of brain inflammation on amyloid-beta clearance mechanisms
  • Chemokines and chemokine receptor signaling in the central nervous system
  • Function of microglial TREM2 signaling on central nervous system health and disease

Significance to patient care

Alzheimer's disease is a devastating neurological disorder that continues to afflict the growing aging population. Dr. Das is determined not only to develop therapies to cure this devastating disease but also to find ways to prevent it for future generations.

Recent Publications

See my publications

Professional Details

Primary Appointment

  1. Molecular Neuroscience

Academic Rank

  1. Assistant Professor of Neuroscience

Education

  1. Research Fellowship - Laboratory of Todd E. Golde, M.D., Ph.D. Neuroscience
  2. Research Fellowship - Laboratory of Chella S. David Department of Immunology
  3. Postdoctoral Research Associate Division of Rheumatology, Wayne State University School of Medicine
  4. Ph.D. - Molecular Biology and Immunology Wayne State University
  5. Pre-Doctoral Research - Advisor: Dr. V. Hari. Department of Biology, Wayne State University
  6. MSc - Cytogenics Utkal University
  7. BSc - Zoology BJB College
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BIO-00027335

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