Location

Rochester, Minnesota

Contact

Abyzov.Alexej@mayo.edu

Summary

Research in the laboratory of Alexej Abyzov, Ph.D., is focused on discovery and analysis of genomic variants and their relevance to diseases. Dr. Abyzov's particular interest is in large variants such as deletions and duplications of thousands and millions of nucleotides in individual genomes. Special emphasis is on discovery and analysis of somatic variants — those originating in human cells during their life span — as they can cause cancer and various diseases.

Focus areas

  • Genomic variant discovery from sequencing
  • Prediction of variant function and impact
  • Somatic variations and single cell genomics
  • Cancer genomics

Significance to patient care

The ability to discover and predict the effects of (interpret) genomic variants allows for personalized medical treatment, such as the treatment of cancer, to make disease management more effective and less disturbing for a patient. The goal of Dr. Abyzov's research is to advance the understanding of genomic variants to such a degree that would allow for proactively identifying individual genetic risks in various diseases, monitoring these risks during the entire life of each patient and improving therapy.

Professional highlights

  • Associate research scientist, Department of Molecular Biophysics and Biochemistry, Yale University, 2011-2012

Recent Publications

See my publications

Professional Details

Academic Rank

  1. Assistant Professor of Medical Informatics

Education

  1. PhD - Computational Biology Northeastern University
  2. MS - Physics Moscow Institute of Physics and Techology
  3. BS - Physics Moscow Institute of Physics and Techology
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BIO-20089449

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