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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 14 for Chronic myeloid leukemia

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  1. Phase 1 Trial To Evaluate The Safety, Pharmacokinetics And Pharmacodynamics Of Splicing Modulator H3B-8800 For Subjects With Myelodysplastic Syndromes, Acute Myeloid Leukemia, And Chronic Myelomonocytic Leukemia

    Jacksonville, FL, Rochester, MN

  2. Safety And Anti-leukemic Activity Of Vodobatinib (K0706) For Treatment Refractory/Intolerant CML Failing ≥3 Prior Chronic Myeloid Leukemia Therapies

    Jacksonville, FL

  3. Nilotinib and Combination Chemotherapy in Treating Patients with Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Blastic Phase Chronic Myelogenous Leukemia

    Scottsdale/Phoenix, AZ, Rochester, MN

  4. Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine As First-Line Treatment For Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML), Or Low-Blast Acute Myelogenous Leukemia (AML)

    Jacksonville, FL

  5. A Study To Evaluate Tacrolimus/Methotrexate Versus Post-Transplant Cyclophosphamide/ Tacrolimus/Mycophenolate Mofetil In Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation

    Jacksonville, FL, Rochester, MN

  6. Tipifarnib In Subjects With Chronic Myelomonocytic Leukemia, Other Myelodysplastic /Myeloproliferative Neoplasias, And Acute Myeloid Leukemia

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. A Study To Evaluate Exercise For Cancer Patients At Risk Of Falling

    Rochester, MN

  8. Phase I Clinical Study Of CWP232291 In Acute Myeloid Leukemia Patients

    Rochester, MN

  9. A Study To Evaluate Pembrolizumab And Dasatinib, Imatinib Mesylate, Or Nilotinib In Treating Patients With Chronic Myeloid Leukemia And Persistently- Detectable Minimal Residual Disease

    Eau Claire, WI, Rochester, MN

  10. Study of US-ATG-F to Prevent Chronic Graft Versus Host Disease (GVHD)

    Rochester, MN

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