Genetics and Model Systems Core

Director: Stephen C. Ekker, Ph.D.

The Genetics and Model Systems Core is a central repository for genetics-based tools and model systems expertise.

Services

Plasmids and other DNA constructs support

  • Design
  • Construction
  • Validation

Expanded zebrafish technical support

Reagents/database

  • Transposons
  • Bacterial artificial chromosomes
  • Custom zinc finger nucleases

Consults and training

  • Bioinformatics
    • Microarray design and analysis
    • Next-generation transcriptome and sequence analysis
  • Biostatistics consults
    • Key experimental design elements (such as a power analysis for sample size estimates) necessary for designing human genetics studies
  • Genetics technologies
    • Rodent and zebrafish transgenic/knockout model development support
    • Viral delivery of siRNA
    • Transposons for somatic genetic engineering
    • In vivo imaging