In the Cancer Immunology and Immunotherapy Program, scientists and physicians from numerous departments across the three Mayo Clinic Cancer Center locations in Scottsdale, Ariz.; Jacksonville, Fla.; and Rochester, Minn., conduct research to advance basic knowledge about how the immune system functions and how it interacts with various types of cancers.

The program's multidisciplinary team of investigators uses that knowledge to develop and test new immunotherapy cancer treatments.

Scientists are revealing that complex molecular and cellular mechanisms regulate the activation of the immune system.

By studying both positive and negative interactions of immune system cells with normal cells and with tumors, Cancer Immunology and Immunotherapy Program researchers are increasing their understanding of why some people have immune systems that fail to recognize tumor cells as foreign, and how some cancers evade detection or even block immune cell functions.

The ultimate goal is to devise novel ways to prevent cancer from developing and treatments that more effectively enable the immune system to kill tumor cells in cancer patients.


The Cancer Immunology and Immunotherapy Program has two co-leaders: