CCaTS: Accelerating discoveries toward better health

Mayo Clinic's Center for Clinical and Translational Science (CCaTS) is funded by the National Institute of Health's (NIH) Clinical and Translational Science Awards (CTSA) program, grant number UL1TR000135, from the National Center for Advancing Translational Sciences (NCATS).

The CTSA program addresses the development and implementation of national standards and best practices for translation, from basic discovery to clinical and community-engaged research. The program supports a national network of medical research institutions collaborating to transform how clinical and translational science is conducted nationwide.

Mayo Clinic CCaTS is led by Sundeep Khosla, M.D., director of CCaTS and principal investigator of the NIH CTSA grant effective June 1, 2013. Dr. Khosla holds a significant Mayo Clinic leadership role as Dean for Clinical and Translational Science. He has extensive research experience in translational research as well as national and institutional administrative experience.

Dr. Khosla is a member of the NCATS CTSA Steering Committee. The Steering Committee plays a central role in the structure of the CTSA program. It assists in coordinating activities conducted by the CTSA consortium — representing 62 hubs — and provides guidance to NCATS leadership. The committee identifies and recommends best practices and policies that will advance clinical and translational research as a discipline and facilitates collaborations among CTSA and non-CTSA institutions, and with partners in clinical and translational research (industry, laboratories, hospitals).

The content of this website is solely the responsibility of the Mayo Clinic CCaTS and does not necessarily represent the official views of the NIH.


Human antibody can delay Lou Gehrig's disease in two mouse models

Researchers at Mayo Clinic and the University of Minnesota have successfully used a single dose of a natural human antibody to delay degeneration of spinal cord neurons in two distinct mouse models of amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease). The study, published in the journal Disease Models & Mechanisms, suggests new possible therapies for patients with ALS, the authors say.

Mayo Clinic-led networks approved for more than $10 million to participate in PCORnet, the National Patient-Centered Clinical Research Network

Two collaborative networks led by Mayo Clinic were approved for three-year funding awards by the Patient-Centered Outcomes Research Institute (PCORI), becoming part of PCORnet, the National Patient-Centered Clinical Research Network.

Meet the 2015 Career Transition Awardees

The Center for Clinical and Translational Science (CCaTS) has announced the 2015 recipients of the Career Transition Award in Clinical/Translational Research.