CCaTS: Accelerating discoveries toward better health
Mayo Clinic's Center for Clinical and Translational Science (CCaTS) is funded by the National Institute of Health's (NIH) Clinical and Translational Science Awards (CTSA) program, grant numbers UL1TR002377, KL2TR0002379 and TL1TR002380 from the National Center for Advancing Translational Sciences (NCATS).
The CTSA program addresses the development and implementation of national standards and best practices for translation, from basic discovery to clinical and community-engaged research. The program supports a national network of medical research institutions collaborating to transform how clinical and translational science is conducted nationwide.
Mayo Clinic CCaTS is led by Sundeep Khosla, M.D., director of CCaTS and principal investigator of the NIH CTSA grant. Dr. Khosla holds a significant Mayo Clinic leadership role as Dean for Clinical and Translational Science. He has extensive research experience in translational research as well as national and institutional administrative experience.
Dr. Khosla is a past member of the NCATS CTSA Steering Committee and active member of the CTSA consortium, which consists of 62 hubs.
Dr. Khosla is joined by David O. Warner, M.D., associate director of CCaTS, co-principal investigator of the UL1TR002377 grant and principal investigator of the mentored career development grant (KL2TR002379), and by Anthony J. Windebank, M.D., principal investigator of the predoctoral training grant (TL1TR002380).
The content of this website is solely the responsibility of the Mayo Clinic CCaTS and does not necessarily represent the official views of the NIH.
National Institutes of Health (NIH) renews Mayo Clinic's Clinical and Translational Research Award
The NIH has renewed one of Mayo Clinic's largest government research grants for five more years, ensuring support for clinical and translational research and training through 2022. The grant supports Mayo researchers in translating discoveries to address unmet patient needs, while engaging physicians and scientists at all levels.
Researchers report link between cells associated with aging and bone loss
Mayo Clinic researchers have reported a causal link between senescent cells — the cells associated with aging and age-related disease — and bone loss in mice. Targeting these cells led to an increase in bone mass and strength. The findings appear online in Nature Medicine.
Mayo Clinic expert addresses bone and mineral scientists
On the road from clinical need to effective therapy, osteoporosis has come a long way. "When I jointed Mayo in 1988, I could offer calcium, vitamin D, estrogen," says Sundeep Khosla, M.D., "and that was pretty much it."