A Study Of Cellular Characterization Of Autologous Serum Eye Drops
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Jacksonville, Florida: 26-002658
About this study
The purpose of this study is to partially characterize the cellular composition of eye drops (ASED) made from the whole blood of healthy individuals to help guide future ASED manufacturing and production and quantify relevant cell types and extracellular vesicles in ASED.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
Subjects, 18 years and older, undergoing routine medical procedures that will have already require venipuncture or IV placement as part of a surgical procedure.
Complete a signed consent form.
Exclusion Criteria:
History of superficial infection within 6 months of study enrollment, or evidence of current superficial infection.
Taking anticoagulant medications (e.g. warfarin, heparin) or clopidogrel (Plavix).
Taking anti-rheumatic disease medication (including methotrexate or other antimetabolites) within 3 months prior to study enrollment.
On chronic, immunosuppressive transplant therapy or having a chronic, immunosuppressive state, including use of systemic steroids/corticosteroids.
Systemic inflammatory, rheumatological or connective tissue disorder including but not limited to rheumatoid arthritis, systemic sclerosis, system lupus erythematosus, and Ehlers-Danlos Syndrome.
Ongoing infectious disease, including but not limited to tuberculosis, HIV, hepatitis, and syphilis.
History of cancer/malignancy with the exception of adequately treated basal cell or squamous cell carcinoma of the skin within the last 5 years.
History of blood dyscrasia, including but not limited to anemia, thrombocytopenia, and monoclonal gammopathy.
Currently pregnant individuals.
Individuals under the age of 18 years old.
Note: Other protocol defined Inclusion/Exclusion Criteria may apply.
Eligibility last updated 03/30/2026. Questions regarding updates should be directed to the study team contact.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Jacksonville, Fla.
Mayo Clinic principal investigator Shane Shapiro, M.D. |
Open for enrollment |
|
More information
Publications
Publications are currently not available