A Study to Investigate the Improvement of Sensitivity of a New Contrast Enhanced Ultrasound (CEUS) Technology Over Those of Traditional CEUS


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 17-006357
    Sponsor Protocol Number: 17-006357

About this study

The overall goal of this study is to investigate the improvement of sensitivity and penetration of a new contrast enhanced ultrasound (CEUS) technology over those of traditional CEUS.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Patients with clinically indicated contrast enhanced echocardiography 
  • Age above 18

Exclusion Criteria:

  • Patients with any adverse reactions to the preceding clinically indicated CEUS imaging 
  • Pregnant women
  • Nursing mother 
  • Patients with known or suspected right-to-left, bi-directional, or transient right-to-left cardiac shunts 
  • Patients with history of hypersensitivity allergic reactions to ultrasound contrast agents 
  • Patients lacking capacity to consent 
  • Vulnerable subjects such as prisoners

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Shigao Chen, Ph.D.

Open for enrollment

Contact information:

Theresa Nielson C.C.R.C.