Acoustic Spectrograms and Detection of Early LVAD Thrombosis


About this study

The purpose of this study is to characterize the acoustic features of normal left ventricular assist device (LVAD) pump function using spectrography and fast Fourier transformation. The study will also identify abnormalities seen in the acoustic spectrograms of those patients presenting with LVAD thrombosis. Furthermore, the study aims to follow patients where abnormalities are seen in order to ascertain which features are predictive of the development of pump thrombosis and may be considered early markers thereof.


Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Status post LVAD implantation (FDA-cleared makes and models implanted at Mayo Clinic Rochester).
  • Patients 18 years of age and greater agreeable with having an acoustic spectrogram taken at the time of their clinic appointment or during their hospitalization.

Exclusion Criteria: 

  • Patient refusal

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Barry Boilson, M.D.

Open for enrollment

Contact information:

Barry Boilson M.D.

More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available