Efficacy and Safety of Early Exercise Program After Acute DVT for Prevention of Post Thrombotic Syndrome


About this study

The pupose of this study is to determine the effect of exercise on patients with an acute deep vein thrombosis.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age 18- 90 years
  • Able to participate in supervised exercise if randomized to this group.
  • Diagnosis of acute DVT (within 24-48 hours) and 24 hours of anticoagulation prior to starting the study.

Exclusion Criteria:

  • Recent major surgery or surgical intervention of the lower extremity wit in the last 3 months.
  • Active malignancy, on treatment with chemo or radiation.
  • Unable to do graded treadmill exercise.
  • Unable to comply with keeping log of activity/exercise.
  • Weight > 300 pounds. (weight limit for the air plethysmography chair)
  • Previous history of DVT or PE.
  • On anticoagulation for another purpose (example stroke prevention with atrial fibrillation)

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Robert McBane, M.D.

Closed for enrollment

Contact information:

Rayya Saadiq D.O.



More information


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