A Study of a New Molecular Approach to Blood DNA Screening for Cancer


About this study

The primary aim of this study is to evaluate the distribution of marker levels determined by this multi-marker, multi-compartment blood DNA test approach across persons without known cancer or precancer.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Must be 18 years of age or older
  • Patients without a known internal (non-cutaneous) cancer or a history of an internal cancer

Exclusion Criteria:

  • Patients has a past or current diagnosis of invasive cancer (this does not include basal cell or squamous cell skin cancers)
  • Patient has had a solid organ transplant
  • Inability to give informed consent

Urine Exclusions

  • Patient has transurethral instrumentation (cystoscopy, placement of urinary catheter) within the 7 days prior to sample collection
  • Patient has chronic indwelling urinary catheter
  • Patient has had a urinary tract infection within the 14 days prior to sample collection

Note: Other protocol defined Inclusion/Exclusion criteria may apply.

Eligibility last updated 12/14/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

John Kisiel, M.D.

Open for enrollment

Contact information:

Anna Gonser CCRP

(507) 538-4883


More information


Publications are currently not available

Additional contact information

Cancer-related trials contact form

Phone: 855-776-0015 (toll-free)

International patient clinical studies questions