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Olfactory and Sinonasal Epithelium as Cell Source of Neural Progenitors and Autologous Constructs

Overview

Acerca de este estudio

The goals of the study are to develop protocols for growing cells isolated from the nasal epithelium and fat tissue. This will be used to help grow nerve-related tissue as well as cartilage, epithelial cells, muscle cells, or other cells that are present in the head and neck region. The goal is to generate a large number of cells that could be used for constructing tissue that can be implanted for structural and functional reconstruction.

The development of such methods is a step in our goal to rehabilitate patients with cancer, trauma, or other debilitating neurological diseases that lose function and structure in the head and neck area. The cells isolated from your tissues will not be used for developing implants but will help with experiments to establish the protocols needed to cultivate cells and develop the implant.

Elegibilidad para participar

Los requisitos de elegibilidad de los participantes incluyen la edad, el sexo, el tipo y el estadio de la enfermedad, y los problemas de salud o tratamientos previos. Las pautas difieren de un estudio a otro e identifican quiénes pueden o no pueden participar. No hay garantía de que cada persona elegible que desee participar en un ensayo se inscribirá. Comunícate con el equipo del estudio para analizar la elegibilidad del estudio y la posible participación.

Inclusion Criteria:

  • This study will enroll patients who are undergoing endoscopic endonasal skull base procedures where nasal tissue and fat is taken as standard of care. Tissue that is removed for creating surgical access, or is left behind after skull base reconstruction is usually discarded as "surgical waste". The research will involve use of this tissue.

 

Ubicaciones participantes de Mayo Clinic

Los estatus de los estudios cambian con frecuencia. Comunícate con el equipo del estudio para obtener la información más actualizada acerca de la posibilidad de participar.

Ubicación de Mayo Clinic Estado

Scottsdale/Phoenix, Ariz.

Investigador principal de Mayo Clinic

Devyani Lal, M.D.

Inscripción cerrada

More information

Publicaciones

Publications are currently not available

Otros temas en investigación

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CLS-20306919

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