Publications

  1. Dube S, Norby B, Pattan V, Lingineni RK, Singh RJ, Carter RE, Basu A, Basu R. Hepatic 11beta-hydroxysteroid dehydrogenase type 1 activity in obesity and type 2 diabetes using a novel triple tracer cortisol technique. Diabetologia. 2014 Jul; 57(7):1446-55. Epub 2014 Apr 26.
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  2. Lee GO, Kosek P, Lima AA, Singh R, Yori PP, Olortegui MP, Lamsam JL, Oliveira DB, Guerrant RL, Kosek M. The Lactulose: Mannitol Diagnostic Test by HPLC and LC-MSMS Platforms: Considerations for Field Studies of Intestinal Barrier Function and Environmental Enteropathy. J Pediatr Gastroenterol Nutr. 2014 Jun 17.
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  3. Ketha H, Kaur S, Grebe SK, Singh RJ. Clinical applications of LC-MS sex steroid assays: evolution of methodologies in the 21st century. Curr Opin Endocrinol Diabetes Obes. 2014 Jun; 21(3):217-26.
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  4. Veldhuis JD, Dyer RB, Trushin SA, Bondar OP, Singh RJ, Klee GG. Immunologic and mass-spectrometric estimates of SHBG concentrations in healthy women. Metabolism. 2014 Jun; 63(6):783-92. Epub 2014 Mar 21.
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  5. Meekins ME, Oberhelman SS, Lee BR, Gardner BM, Cha SS, Singh RJ, Pettifor JM, Fischer PR, Thacher TD. Pharmacokinetics of daily versus monthly vitamin D3 supplementation in non-lactating women. Eur J Clin Nutr. 2014 May; 68(5):632-4. Epub 2014 Jan 15.
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  6. Klee EW, Bondar OP, Goodmanson MK, Trushin SA, Singh RJ, Anderson NL, Klee GG. Mass spectrometry measurements of prostate-specific antigen (PSA) peptides derived from immune-extracted PSA provide a potential strategy for harmonizing immunoassay differences. Am J Clin Pathol. 2014 Apr; 141(4):527-33.
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  7. Veldhuis JD, Bondar OP, Dyer RB, Trushin SA, Klee EW, Singh RJ, Klee GG. Immunological and mass spectrometric assays of SHBG: consistent and inconsistent metabolic associations in healthy men. J Clin Endocrinol Metab. 2014 Jan; 99(1):184-93. Epub 2013 Dec 20
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  8. Dube S, Norby B, Pattan V, Lingineni RK, Singh RJ, Carter RE, Basu A, Basu R. Hepatic 11 beta-hydroxysteroid dehydrogenase type 1 activity in obesity and type 2 diabetes using a novel triple tracer cortisol technique. Diabetologia. 2014; 57(7):1446-55.
  9. Oberhelman SS, Meekins ME, Fischer PR, Lee BR, Singh RJ, Cha SS, Gardner BM, Pettifor JM, Croghan IT, Thacher TD. Maternal vitamin D supplementation to improve the vitamin D status of breast-fed infants: a randomized controlled trial. Mayo Clin Proc. 2013 Dec; 88(12):1378-87.
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  10. Tolan NV, Vidal-Folch N, Algeciras-Schimnich A, Singh RJ, Grebe SK. Individualized correction of neuron-specific enolase (NSE) measurement in hemolyzed serum samples. Clin Chim Acta. 2013 Sep 23; 424:216-21. Epub 2013 Jun 15.
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  11. Torres-Santiago L, Mericq V, Taboada M, Unanue N, Klein KO, Singh R, Hossain J, Santen RJ, Ross JL, Mauras N. Metabolic effects of oral versus transdermal 17beta-estradiol (E(2)): a randomized clinical trial in girls with Turner syndrome. J Clin Endocrinol Metab. 2013 Jul; 98(7):2716-24. Epub 2013 May 15.
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  12. Cipriani C, Romagnoli E, Pepe J, Russo S, Carlucci L, Piemonte S, Nieddu L, McMahon DJ, Singh R, Minisola S. Long-term bioavailability after a single oral or intramuscular administration of 600,000 IU of ergocalciferol or cholecalciferol: implications for treatment and prophylaxis. J Clin Endocrinol Metab. 2013 Jul; 98(7):2709-15. Epub 2013 Jun 13.
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  13. Ryan ZC, Ketha H, McNulty MS, McGee-Lawrence M, Craig TA, Grande JP, Westendorf JJ, Singh RJ, Kumar R. Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium. Proc Natl Acad Sci U S A. 2013 Apr 9; 110(15):6199-204. Epub 2013 Mar 25.
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  14. Sood R, Warndahl RA, Schroeder DR, Singh RJ, Rhodes DJ, Wahner-Roedler D, Bahn RS, Shuster LT. Bioidentical compounded hormones: a pharmacokinetic evaluation in a randomized clinical trial. Maturitas. 2013 Apr; 74(4):375-82. Epub 2013 Feb 04.
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  15. Basaria S, Davda MN, Travison TG, Ulloor J, Singh R, Bhasin S. Risk factors associated with cardiovascular events during testosterone administration in older men with mobility limitation. J Gerontol A Biol Sci Med Sci. 2013 Feb; 68(2):153-60. Epub 2012 May 04.
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  16. Thacher TD, Fischer PR, Tebben PJ, Singh RJ, Cha SS, Maxson JA, Yawn BP. Increasing incidence of nutritional rickets: a population-based study in Olmsted County, Minnesota. Mayo Clin Proc. 2013 Feb; 88(2):176-83.
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  17. Kasahara AK, Singh RJ, Noymer A. Vitamin D (25OHD) Serum Seasonality in the United States. PLoS One. 2013; 8(6):e65785. Epub 2013 Jun 21.
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  18. Craig TA, Zhang Y, McNulty MS, Middha S, Ketha H, Singh RJ, Magis AT, Funk C, Price ND, Ekker SC, Kumar R. Research resource: whole transcriptome RNA sequencing detects multiple 1alpha,25-dihydroxyvitamin D(3)-sensitive metabolic pathways in developing zebrafish. Mol Endocrinol. 2012 Sep; 26(9):1630-42. Epub 2012 Jun 25
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  19. Hagan JB, Netzel BC, Matthews MR, Korpi-Steiner NL, Singh RJ. Urinary fluticasone propionate-17beta-carboxylic acid to assess asthma therapy adherence. Allergy Asthma Proc. 2012 Jul-Aug; 33(4):e35-9.
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  20. Bancos I, Grant CS, Nadeem S, Stan MN, Reading CC, Sebo TJ, Algeciras-Schimnich A, Singh RJ, Dean DS. Risks and benefits of parathyroid fine-needle aspiration with parathyroid hormone washout. Endocr Pract. 2012 Jul-Aug; 18(4):441-9.
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  21. Kovacs K, Wagley S, Quirk MT, Ceron OM, Silva PA, Singh RJ, Gukasyan HJ, Arroyo JG. Pharmacokinetic study of vitreous and serum concentrations of triamcinolone acetonide after posterior sub-tenon's injection. Am J Ophthalmol. 2012 May; 153(5):939-48. Epub 2012 Feb 04.
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  22. Erickson D, Singh RJ, Sathananthan A, Vella A, Bryant SC. Late-night salivary cortisol for diagnosis of Cushing's syndrome by liquid chromatography/tandem mass spectrometry assay. Clin Endocrinol (Oxf). 2012 Apr; 76(4):467-72.
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  23. Bhasin S, Travison TG, Storer TW, Lakshman K, Kaushik M, Mazer NA, Ngyuen AH, Davda MN, Jara H, Aakil A, Anderson S, Knapp PE, Hanka S, Mohammed N, Daou P, Miciek R, Ulloor J, Zhang A, Brooks B, Orwoll K, Hede-Brierley L, Eder R, Elmi A, Bhasin G, Effect of testosterone supplementation with and without a dual 5alpha-reductase inhibitor on fat-free mass in men with suppressed testosterone production: a randomized controlled trial. JAMA. 2012 Mar 7; 307(9):931-9.
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  24. Tebben PJ, Milliner DS, Horst RL, Harris PC, Singh RJ, Wu Y, Foreman JW, Chelminski PR, Kumar R. Hypercalcemia, hypercalciuria, and elevated calcitriol concentrations with autosomal dominant transmission due to CYP24A1 mutations: effects of ketoconazole therapy. J Clin Endocrinol Metab. 2012 Mar; 97(3):E423-7. Epub 2012 Feb 15.
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  25. Taboada M, Santen R, Lima J, Hossain J, Singh R, Oerter Klein K, Mauras N. Pharmacokinetics and pharmacodynamics of oral and transdermal 17beta estradiol in girls with turner syndrome. Obstet Gynecol Surv. 2012; 67(4):230-1.
  26. Aguirre Castaneda R, Nader N, Weaver A, Singh R, Kumar S. Response to vitamin D3 supplementation in obese and non-obese Caucasian adolescents. Horm Res Paediatr. 2012; 78(4):226-31. Epub 2012 Oct 31.
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  27. Barna BP, Culver DA, Kanchwala A, Singh RJ, Huizar I, Abraham S, Malur A, Marshall I, Kavuru MS, Thomassen MJ. Alveolar macrophage cathelicidin deficiency in severe sarcoidosis. J Innate Immun. 2012; 4(5-6):569-78. Epub 2012 Jul 03.
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  28. Taboada M, Santen R, Lima J, Hossain J, Singh R, Klein KO, Mauras N. Pharmacokinetics and pharmacodynamics of oral and transdermal 17beta estradiol in girls with Turner syndrome. J Clin Endocrinol Metab. 2011 Nov; 96(11):3502-10. Epub 2011 Aug 31.
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  29. Rao AS, Camilleri M, Eckert DJ, Busciglio I, Burton DD, Ryks M, Wong BS, Lamsam J, Singh R, Zinsmeister AR. Urine sugars for in vivo gut permeability: validation and comparisons in irritable bowel syndrome-diarrhea and controls. Am J Physiol Gastrointest Liver Physiol. 2011 Nov; 301(5):G919-28. Epub 2011 Aug 11.
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  30. Kleerekoper M, Schleicher RL, Eisman J, Bouillon R, Singh RJ, Holick MF. Clinical applications for vitamin D assays: what is known and what is wished for. Clin Chem. 2011 Sep; 57(9):1227-32. Epub 2011 Apr 18.
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  31. Bhasin S, Pencina M, Jasuja GK, Travison TG, Coviello A, Orwoll E, Wang PY, Nielson C, Wu F, Tajar A, Labrie F, Vesper H, Zhang A, Ulloor J, Singh R, D'Agostino R, Vasan RS. Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese young men in the Framingham Heart Study and applied to three geographically distinct cohorts. J Clin Endocrinol Metab. 2011 Aug; 96(8):2430-9. Epub 2011 Jun 22.
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  32. McNulty M, Singh RJ, Li X, Bergstralh EJ, Kumar R. Determination of serum and plasma sclerostin concentrations by enzyme-linked immunoassays. J Clin Endocrinol Metab. 2011 Jul; 96(7):E1159-62. Epub 2011 May 04.
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  33. Hagan JB, Taylor RL, Kita H, Singh RJ. Analysis of fluticasone propionate in induced sputum by mass spectrometry. Allergy Asthma Proc. 2011 Jul-Aug; 32(4):18-21.
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  34. Netzel BC, Cradic KW, Bro ET, Girtman AB, Cyr RC, Singh RJ, Grebe SK. Increasing liquid chromatography-tandem mass spectrometry throughput by mass tagging: a sample-multiplexed high-throughput assay for 25-hydroxyvitamin D2 and D3. Clin Chem. 2011 Mar; 57(3):431-40. Epub 2011 Jan 18.
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  35. Kunisaki KM, Niewoehner DE, Singh RJ, Connett JE. Vitamin D status and longitudinal lung function decline in the Lung Health Study. Eur Respir J. 2011 Feb; 37(2):238-43. Epub 2010 Jul 01.
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  36. Hackbarth JS, Hoyne JB, Grebe SK, Singh RJ. Accuracy of calculated free testosterone differs between equations and depends on gender and SHBG concentration. Steroids. 2011 Jan; 76(1-2):48-55.
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  37. Pruthi S, Haakenson C, Brost BC, Bryant K, Reid JM, Singh R, Netzel B, Boughey JC, Degnim AC. Pharmacokinetics of methylene blue dye for lymphatic mapping in breast cancer-implications for use in pregnancy. Am J Surg. 2011 Jan; 201(1):70-5.
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  38. Sarafoglou K, Himes JH, Lacey JM, Netzel BC, Singh RJ, Matern D. Comparison of multiple steroid concentrations in serum and dried blood spots throughout the day of patients with congenital adrenal hyperplasia. Horm Res Paediatr. 2011; 75(1):19-25. Epub 2010 Aug 25
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  39. Nader NS, Bahn RS, Johnson MD, Weaver AL, Singh R, Kumar S. Relationships between thyroid function and lipid status or insulin resistance in a pediatric population. Thyroid. 2010 Dec; 20(12):1333-9.
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  40. Rao AS, Wong BS, Camilleri M, Odunsi-Shiyanbade ST, McKinzie S, Ryks M, Burton D, Carlson P, Lamsam J, Singh R, Zinsmeister AR. Chenodeoxycholate in females with irritable bowel syndrome-constipation: a pharmacodynamic and pharmacogenetic analysis. Gastroenterology. 2010 Nov; 139(5):1549-58, 1558.e1. Epub 2010 Aug 04.
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  41. Zerikly RK, Amiri L, Faiman C, Gupta M, Singh RJ, Nutter B, Kennedy L, Hatipoglu B, Weil RJ, Hamrahian AH. Diagnostic characteristics of late-night salivary cortisol using liquid chromatography-tandem mass spectrometry. J Clin Endocrinol Metab. 2010 Oct; 95(10):4555-9. Epub 2010 Jul 14.
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  42. Drake MT, Maurer MJ, Link BK, Habermann TM, Ansell SM, Micallef IN, Kelly JL, Macon WR, Nowakowski GS, Inwards DJ, Johnston PB, Singh RJ, Allmer C, Slager SL, Weiner GJ, Witzig TE, Cerhan JR. Vitamin D insufficiency and prognosis in non-Hodgkin's lymphoma. J Clin Oncol. 2010 Sep 20; 28(27):4191-8. Epub 2010 Aug 16.
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  43. Lodish MB, Adams KT, Huynh TT, Prodanov T, Ling A, Chen C, Shusterman S, Jimenez C, Merino M, Hughes M, Cradic KW, Milosevic D, Singh RJ, Stratakis CA, Pacak K. Succinate dehydrogenase gene mutations are strongly associated with paraganglioma of the organ of Zuckerkandl. Endocr Relat Cancer. 2010 Sep; 17(3):581-8. Epub 2010 Jun 03.
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  44. Thacher TD, Fischer PR, Obadofin MO, Levine MA, Singh RJ, Pettifor JM. Comparison of metabolism of vitamins D-2 and D-3 in children with nutritional rickets. J Bone Miner Res. 2010 Sep; 25(9):1988-95.
  45. Thacher TD, Fischer PR, Obadofin MO, Levine MA, Singh RJ, Pettifor JM. Comparison of metabolism of vitamins D2 and D3 in children with nutritional rickets. J Bone Miner Res. 2010 Sep; 25(9):1988-95.
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  46. Hagan JB, Erickson D, Singh RJ. Triamcinolone acetonide induced secondary adrenal insufficiency related to impaired CYP3A4 metabolism by coadministration of nefazodone. Pain Med. 2010 Jul; 11(7):1132-5. Epub 2010 Apr 29.
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  47. Lee S, Kwon S, Shin HJ, Lim HS, Singh RJ, Lee KR, Kim YJ. Simultaneous quantitative analysis of salivary cortisol and cortisone in Korean adults using LC-MS/MS. BMB Rep. 2010 Jul; 43(7):506-11.
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  48. Anderson H, Fogel N, Grebe SK, Singh RJ, Taylor RL, Dunaif A. Infants of women with polycystic ovary syndrome have lower cord blood androstenedione and estradiol levels. J Clin Endocrinol Metab. 2010 May; 95(5):2180-6. Epub 2010 Mar 12.
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  49. Johnson MD, Nader NS, Weaver AL, Singh R, Kumar S. Relationships between 25-hydroxyvitamin D levels and plasma glucose and lipid levels in pediatric outpatients. J Pediatr. 2010 Mar; 156(3):444-9. Epub 2009 Nov 18.
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  50. Odunsi-Shiyanbade ST, Camilleri M, McKinzie S, Burton D, Carlson P, Busciglio IA, Lamsam J, Singh R, Zinsmeister AR. Effects of chenodeoxycholate and a bile acid sequestrant, colesevelam, on intestinal transit and bowel function. Clin Gastroenterol Hepatol. 2010 Feb; 8(2):159-65. Epub 2009 Oct 30.
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  51. Kumar V, Barnidge DR, Chen LS, Twentyman JM, Cradic KW, Grebe SK, Singh RJ. Quantification of serum 1-84 parathyroid hormone in patients with hyperparathyroidism by immunocapture in situ digestion liquid chromatography-tandem mass spectrometry. Clin Chem. 2010 Feb; 56(2):306-13. Epub 2009 Dec 10.
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  52. Lopez MF, Rezai T, Sarracino DA, Prakash A, Krastins B, Athanas M, Singh RJ, Barnidge DR, Oran P, Borges C, Nelson RW. Selected reaction monitoring-mass spectrometric immunoassay responsive to parathyroid hormone and related variants. Clin Chem. 2010 Feb; 56(2):281-90. Epub 2009 Dec 18.
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  53. Camilleri M, Nadeau A, Lamsam J, Nord SL, Ryks M, Burton D, Sweetser S, Zinsmeister AR, Singh R. Understanding measurements of intestinal permeability in healthy humans with urine lactulose and mannitol excretion. Neurogastroenterol Motil. 2010 Jan; 22(1):e15-26. Epub 2009 Jul 13
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  54. Korpi-Steiner NL, Netzel BC, Seegmiller JC, Hagan JB, Singh RJ. Liquid chromatography-tandem mass spectrometry analysis of urinary fluticasone propionate-17beta-carboxylic acid for monitoring compliance with inhaled-fluticasone propionate therapy. Steroids. 2010 Jan; 75(1):77-82. Epub 2009 Oct 31.
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  55. Singh RJ. Quantitation of 25-OH-vitamin D (25OHD) using liquid tandem mass spectrometry (LC-MS-MS). Methods Mol Biol. 2010; 603:509-17.
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  56. Singh RJ. Quantitation of 17-OH-progesterone (OHPG) for diagnosis of congenital adrenal hyperplasia (CAH). Methods Mol Biol. 2010; 603:271-7.
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  57. Diabetes Research in Children Network (DirecNet) Study Group, Tsalikian E, Tamborlane W, Xing D, Becker DM, Mauras N, Fiallo-Scharer R, Buckingham B, Weinzimer S, Steffes M, Singh R, Beck R, Ruedy K, Kollman C. Blunted counterregulatory hormone responses to hypoglycemia in young children and adolescents with well-controlled type 1 diabetes. Diabetes Care. 2009 Nov; 32(11):1954-9. Epub 2009 Aug 12.
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  58. Camilleri M, Nadeau A, Tremaine WJ, Lamsam J, Burton D, Odunsi S, Sweetser S, Singh R. Measurement of serum 7alpha-hydroxy-4-cholesten-3-one (or 7alphaC4), a surrogate test for bile acid malabsorption in health, ileal disease and irritable bowel syndrome using liquid chromatography-tandem mass spectrometry. Neurogastroenterol Motil. 2009 Jul; 21(7):734-e43. Epub 2009 Mar 13.
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  59. Vesper HW, Bhasin S, Wang C, Tai SS, Dodge LA, Singh RJ, Nelson J, Ohorodnik S, Clarke NJ, Salameh WA, Parker CR Jr, Razdan R, Monsell EA, Myers GL. Interlaboratory comparison study of serum total testosterone [corrected] measurements performed by mass spectrometry methods. Steroids. 2009 Jun; 74(6):498-503. Epub 2009 Jan 30.
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  60. Silva PS, Singh RJ, Bakri SJ, Lising RS, Santiago DE, Uy HS. Vitreous concentration of triamcinolone acetonide after a single transseptal depot injection. Ocul Immunol Inflamm. 2009 May-Jun; 17(3):216-20.
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  61. Basu R, Basu A, Grudzien M, Jung P, Jacobson P, Johnson M, Singh R, Sarr M, Rizza RA. Liver is the site of splanchnic cortisol production in obese nondiabetic humans. Diabetes. 2009 Jan; 58(1):39-45. Epub 2008 Oct 13.
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  62. Singh RJ. Validation of a high throughput method for serum/plasma testosterone using liquid chromatography tandem mass spectrometry (LC-MS/MS). Steroids. 2008 Dec 12; 73(13):1339-44. Epub 2008 Jul 25.
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  63. Bhasin S, Zhang A, Coviello A, Jasuja R, Ulloor J, Singh R, Vesper H, Vasan RS. The impact of assay quality and reference ranges on clinical decision making in the diagnosis of androgen disorders. Steroids. 2008 Dec 12; 73(13):1311-7. Epub 2008 Jul 17.
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  64. Santen RJ, Lee JS, Wang S, Demers LM, Mauras N, Wang H, Singh R. Potential role of ultra-sensitive estradiol assays in estimating the risk of breast cancer and fractures. Steroids. 2008 Dec 12; 73(13):1318-21. Epub 2008 Jul 09.
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  65. Liu Y, Singh RJ, Usa K, Netzel BC, Liang M. Renal medullary 11 beta-hydroxysteroid dehydrogenase type 1 in Dahl salt-sensitive hypertension. Physiol Genomics. 2008 Dec 12; 36(1):52-8. Epub 2008 Sep 30.
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  66. Singh RJ. Improving Patient Care with Tandem Mass Spectrometry. Clin Lab News. 2008 Dec; 34(12):52-54 Epub 2008 Dec.
  67. Khosla S, Amin S, Singh RJ, Atkinson EJ, Melton LJ 3rd, Riggs BL. Comparison of sex steroid measurements in men by immunoassay versus mass spectroscopy and relationships with cortical and trabecular volumetric bone mineral density. Osteoporos Int. 2008 Oct; 19(10):1465-71. Epub 2008 Mar 13.
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  68. Shaikh A, Seegmiller JC, Borland TM, Burns BE, Ladwig PM, Singh RJ, Kumar R, Larson TS, Lieske JC. Comparison between immunoturbidimetry, size-exclusion chromatography, and LC-MS to quantify urinary albumin. Clin Chem. 2008 Sep; 54(9):1504-10. Epub 2008 Jul 10.
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  69. Gross KL, Westberry JM, Hubler TR, Sadosky PW, Singh RJ, Taylor RL, Scammell JG. Androgen resistance in squirrel monkeys (Saimiri spp.). Comp Med. 2008 Aug; 58(4):381-8.
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  70. Guo T, Gu J, Soldin OP, Singh RJ, Soldin SJ. Rapid measurement of estrogens and their metabolites in human serum by liquid chromatography-tandem mass spectrometry without derivatization. Clin Biochem. 2008 Jun; 41(9):736-41. Epub 2008 Mar 07.
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  71. Mauras N, Gonzalez de Pijem L, Hsiang HY, Desrosiers P, Rapaport R, Schwartz ID, Klein KO, Singh RJ, Miyamoto A, Bishop K. Anastrozole increases predicted adult height of short adolescent males treated with growth hormone: a randomized, placebo-controlled, multicenter trial for one to three years. J Clin Endocrinol Metab. 2008 Mar; 93(3):823-31. Epub 2007 Dec 28.
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  72. Liu Y, Park F, Pietrusz JL, Jia G, Singh RJ, Netzel BC, Liang M. Suppression of 11beta-hydroxysteroid dehydrogenase type 1 with RNA interference substantially attenuates 3T3-L1 adipogenesis. Physiol Genomics. 2008 Feb 19; 32(3):343-51. Epub 2007 Dec 11.
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  73. Chang SC, Thibodeaux JR, Eastvold ML, Ehresman DJ, Bjork JA, Froehlich JW, Lau C, Singh RJ, Wallace KB, Butenhoff JL. Thyroid hormone status and pituitary function in adult rats given oral doses of perfluorooctanesulfonate (PFOS). Toxicology. 2008 Jan 20; 243(3):330-9. Epub 2007 Oct 26.
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  74. Algeciras-Schimnich A, Preissner CM, Young WF Jr, Singh RJ, Grebe SK. Plasma chromogranin A or urine fractionated metanephrines follow-up testing improves the diagnostic accuracy of plasma fractionated metanephrines for pheochromocytoma. J Clin Endocrinol Metab. 2008 Jan; 93(1):91-5. Epub 2007 Oct 16.
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  75. Englert RC, Dauser D, Gilchrist A, Samociuk HA, Singh RJ, Kesner JS, Cuthbert CD, Zarfos K, Gregorio DI, Stevens RG. Marital status and variability in cortisol excretion in postmenopausal women. Biol Psychol. 2008 Jan; 77(1):32-8. Epub 2007 Sep 02.
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  76. Singh R, Bruton J, Quantitative Analysis of Testosterone in Serum by LC-MS/MS. Quantitative Analysis of Testosterone in Serum by LC-MS/MS. Thermo Scientific. 2008.
  77. Bakri SJ, Snyder MR, Reid JM, Pulido JS, Ezzat MK, Singh RJ. Pharmacokinetics of intravitreal ranibizumab (Lucentis). Ophthalmology. 2007 Dec; 114(12):2179-82.
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  78. Snozek CL, Chambers EP, Reading CC, Sebo TJ, Sistrunk JW, Singh RJ, Grebe SK. Serum thyroglobulin, high-resolution ultrasound, and lymph node thyroglobulin in diagnosis of differentiated thyroid carcinoma nodal metastases. J Clin Endocrinol Metab. 2007 Nov; 92(11):4278-81. Epub 2007 Aug 7.
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  79. Usa K, Singh RJ, Netzel BC, Liu Y, Raff H, Liang M. Renal interstitial corticosterone and 11-dehydrocorticosterone in conscious rats. Am J Physiol Renal Physiol. 2007 Jul; 293(1):F186-92. Epub 2007 Mar 27.
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  80. Chang SC, Thibodeaux JR, Eastvold ML, Ehresman DJ, Bjork JA, Froehlich JW, Lau CS, Singh RJ, Wallace KB, Butenhoff JL. Negative bias from analog methods used in the analysis of free thyroxine in rat serum containing perfluorooctanesulfonate (PFOS). Toxicology. 2007 May 5; 234(1-2):21-33.
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  81. Perry CG, Sawka AM, Singh R, Thabane L, Bajnarek J, Young WF Jr. The diagnostic efficacy of urinary fractionated metanephrines measured by tandem mass spectrometry in detection of pheochromocytoma. Clin Endocrinol (Oxf) 2007 May; 66(5):703-8.
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  82. Bakri SJ, Snyder MR, Reid JM, Pulido JS, Singh RJ. Pharmacokinetics of intravitreal bevacizumab (Avastin). Ophthalmology. 2007 May; 114(5):855-9.
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  83. Kidambi S, Kotchen JM, Grim CE, Raff H, Mao J, Singh RJ, Kotchen TA. Association of adrenal steroids with hypertension and the metabolic syndrome in blacks. Hypertension. 2007 Mar; 49(3):704-11.
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  84. Chase PH, Fiallo-Scharer R, Fisher JH, Tallant B, Tsalikian E, Tansey MJ, Larson LF, Coffey J, Wysocki T, Mauras N, Fox LA, Bird K, Lofton KL, Buckingham BA, Wilson DM, Block JM, Clinton P, Weinzimer SA, Tamborlane WV, Doyle EA, Sikes K, Beck RW, Ruedy Impaired overnight counterregulatory hormone responses to spontaneous hypoglycemia in children with type 1 diabetes. Pediatr Diabetes. 2007; 8(4):199-205.
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  85. Singh RJ. Diagnosing hypercortisolism. MLO Med Lab Obs. 2006 Dec; 38(12):20.
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  86. Babic N, Larson TS, Grebe SK, Turner ST, Kumar R, Singh RJ. Application of liquid chromatography-mass spectrometry technology for early detection of microalbuminuria in patients with kidney disease. Clin Chem. 2006 Nov; 52(11):2155-7.
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  87. Basu R, Edgerton DS, Singh RJ, Cherrington A, Rizza RA. Splanchnic cortisol production in dogs occurs primarily in the liver: evidence for substantial hepatic specific 11beta hydroxysteroid dehydrogenase type 1 activity. Diabetes. 2006 Nov; 55(11):3013-9.
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  88. Guo T, Taylor RL, Singh RJ, Soldin SJ. Simultaneous determination of 12 steroids by isotope dilution liquid chromatography-photospray ionization tandem mass spectrometry. Clin Chim Acta. 2006 Oct; 372(1-2):76-82. Epub 2006 Apr 03.
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  89. Singh RJ, Taylor RL, Reddy GS, Grebe SK. C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of vitamin D status. J Clin Endocrinol Metab. 2006 Aug; 91(8):3055-61. Epub 2006 May 23.
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  90. Bakri SJ, Snyder MR, Pulido JS, McCannel CA, Weiss WT, Singh RJ. Six-month stability of bevacizumab (Avastin) binding to vascular endothelial growth factor after withdrawal into a syringe and refrigeration or freezing. Retina. 2006 May-Jun; 26(5):519-22.
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  91. Eastvold ML, Wallinder HW, Preissner CM, Singh RJ, Lowbeer C, Grebe SK. A two-center international evaluation of the Immulite 2000 automated serum gastrin assay. Clin Biochem. 2006 Apr; 39(4):387-90. Epub 2006 Feb 07.
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  92. Scammell JG, Westberry JM, Sadosky PW, Hubler TR, Williams LE, Gibson SV, Singh RJ, Taylor RL, Shackleton CH. Cortisol metabolism in the Bolivian squirrel monkey (Saimiri boliviensis boliviensis). Comp Med. 2006 Apr; 56(2):128-35.
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  93. Basu R, Singh R, Basu A, Johnson CM, Rizza RA. Effect of nutrient ingestion on total-body and splanchnic cortisol production in humans. Diabetes. 2006 Mar; 55(3):667-74.
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  94. Costello P, Bakri SJ, Beer PM, Singh RJ, Falk NS, Peters GB, Melendez JA. Vitreous penetration of topical moxifloxacin and gatifloxacin in humans. Retina. 2006 Feb; 26(2):191-5.
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  95. Toran-Allerand CD, Tinnikov AA, Singh RJ, Nethrapalli IS. 17 alpha-estradiol: A brain-active estrogen? Endocrinology. 2005 Sep; 146(9):3843-50.
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  96. Basu R, Singh RJ, Basu A, Chittilapilly EG, Johnson MC, Toffolo G, Cobelli C, Rizza RA. Obesity and type 2 diabetes do not alter splanchnic cortisol production in humans. J Clin Endocrinol Metab. 2005 Jul; 90(7):3919-26. Epub 2005 Apr 05.
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  97. Rajamannan NM, Subramaniam M, Stock SR, Stone NJ, Springett M, Ignatiev KI, McConnell JP, Singh RJ, Bonow RO, Spelsberg TC. Atorvastatin inhibits calcification and enhances nitric oxide synthase production in the hypercholesterolaemic aortic valve. Heart (British Cardiac Society) 2005 Jun; 91(6):806-10.
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  98. Tebben PJ, Kalli KR, Cliby WA, Hartmann LC, Grande JP, Singh RJ, Kumar R. Elevated fibroblast growth factor 23 in women with malignant ovarian tumors. Mayo Clin Proc. 2005 Jun; 80(6):745-51.
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  99. Short KR, Bigelow ML, Kahl J, Singh R, Coenen-Schimke J, Raghavakaimal S, Nair KS. Decline in skeletal muscle mitochondrial function with aging in humans. Proc Natl Acad Sci U S A. 2005 Apr 12; 102(15):5618-23. Epub 2005 Mar 30.
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  100. Gomez EA, Ehresmann DD, Ledebuhr LK, Eastvold ML, Singh RJ, Klee GG, Grebe SK. Development and validation of an automated chemiluminometric immunoassay for human intrinsic factor antibodies in serum. Clin Chem. 2005 Jan; 51(1):232-5.
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  101. Preissner CM, Dodge LA, O'Kane DJ, Singh RJ, Grebe SK. Prevalence of heterophilic antibody interference in eight automated tumor marker immunoassays. Clin Chem. 2005 Jan; 51(1):208-10.
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  102. Mason JO, Somaiya MD, Singh RJ. Intravitreal concentration and clearance of triamcinolone acetonide in nonvitrectomized human eyes. Retina: the Journal of Retinal & Vitreous Diseases. 2004 Dec; 24(6):900-4.
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  103. Taylor RL, Grebe SK, Singh RJ. Quantitative, highly sensitive liquid chromatography-tandem mass spectrometry method for detection of synthetic corticosteroids. Clin Chem. 2004 Dec; 50(12):2345-52.
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  104. Tebben PJ, Singh RJ, Clarke BL, Kumar R. Fibroblast growth factor 23, parathyroid hormone, and 1alpha,25-dihydroxyvitamin D in surgically treated primary hyperparathyroidism. Mayo Clin Proc. 2004 Dec; 79(12):1508-13.
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  105. Svatikova A, Wolk R, Wang HH, Otto ME, Bybee KA, Singh RJ, Somers VK. Circulating free nitrotyrosine in obstructive sleep apnea. Am J Physiol Regul Integr Comp Physiol. 2004 Aug; 287(2):R284-7. Epub 2004 May 13.
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  106. Basu R, Singh RJ, Basu A, Chittilapilly EG, Johnson CM, Toffolo G, Cobelli C, Rizza RA. Splanchnic cortisol production occurs in humans: evidence for conversion of cortisone to cortisol via the 11-beta hydroxysteroid dehydrogenase (11beta-hsd) type 1 pathway. Diabetes. 2004 Aug; 53(8):2051-9.
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  107. Preissner CM, Reilly WM, Cyr RC, O'Kane DJ, Singh RJ, Grebe SK. Plastic versus glass tubes: effects on analytical performance of selected serum and plasma hormone assays. Clin Chem. 2004 Jul; 50(7):1245-7.
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  108. Cradic KW, Wells JE, Allen L, Kruckeberg KE, Singh RJ, Grebe SK. Substitution of 3'-phosphate cap with a carbon-based blocker reduces the possibility of fluorescence resonance energy transfer probe failure in real-time PCR assays. Clin Chem. 2004 Jun; 50(6):1080-2.
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  109. Kumar S, Singh RJ, Reed AM, Lteif AN. Cushing's syndrome after intra-articular and intradermal administration of triamcinolone acetonide in three pediatric patients. Pediatrics. 2004 Jun; 113(6):1820-4.
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  110. Lagerstedt SA, O'Kane DJ, Singh RJ. Measurement of plasma free metanephrine and normetanephrine by liquid chromatography-tandem mass spectrometry for diagnosis of pheochromocytoma. Clin Chem. 2004 Mar; 50(3):603-11. Epub 2004 Jan 15.
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  111. Singh RJ. Advances in metanephrine testing for the diagnosis of pheochromocytoma. Clin Lab Med. 2004 Mar; 24(1):85-103.
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  112. Nelson RE, Grebe SK, OKane DJ, Singh RJ. Liquid chromatography-tandem mass spectrometry assay for simultaneous measurement of estradiol and estrone in human plasma. Clin Chem. 2004 Feb; 50(2):373-84. Epub 2003 Dec 04.
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  113. Singh RJ, Kumar R. Fibroblast growth factor 23 concentrations in humoral hypercalcemia of malignancy and hyperparathyroidism. Mayo Clin Proc. 2003 Jul; 78(7):826-9.
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  114. Preissner CM, O'Kane DJ, Singh RJ, Morris JC, Grebe SKG. Phantoms in the assay tube: Heterophile antibody interferences in serum thyroglobulin assays. J Clin Endocrinol Metab. 2003 Jul; 88(7):3069-74.
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  115. Sawka AM, Jaeschke R, Singh RJ, Young WF. A comparison of biochemical tests for pheochromocytoma: Measurement of fractionated plasma metanephrines compared with the combination of 24-hour urinary metanephrines and catecholamines. J Clin Endocrinol Metab. 2003 Feb; 88(2):553-8.
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  116. Taylor RL, Machacek D, Singh RJ. Validation of a high-throughput liquid chromatography-tandem mass spectrometry method for urinary cortisol and cortisone. Clin Chem. 2002 Sep; 48(9):1511-9.
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  117. Rajamannan NM, Subramaniam M, Springett M, Sebo TC, Niekrasz M, McConnell JP, Singh RJ, Stone NJ, Bonow RO, Spelsberg TC. Atorvastatin inhibits hypercholesterolemia-induced cellular proliferation and bone matrix production in the rabbit aortic valve. Circulation. 2002 Jun 4; 105(22):2660-5.
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  118. Sato J, O'Brien T, Katusic ZS, Fu A, Nygren J, Singh R, Nair KS. Dietary antioxidants preserve endothelium dependent vasorelaxation in overfed rats. Atherosclerosis. 2002 Apr; 161(2):327-33.
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  119. Taylor RL, Singh RJ. Validation of liquid chromatography-tandem mass spectrometry method for analysis of urinary conjugated metanephrine and normetanephrine for screening of pheochromocytoma. Clin Chem. 2002 Mar; 48(3):533-9.
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  120. Sawka AM, Singh RJ, Young WF. False positive biochemical testing for pheochromocytoma caused by surreptitious catecholamine addition to urine. Endocrinologist. 2001 Sep-Oct; 11(5):421-423.
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  121. Sawka AM, Singh RJ, Hiddinga HJ, McConnell JP, Eberhardt NL, Caplice NM, O'Brien T. Remnant lipoproteins induce endothelial plasminogen activator inhibitor-1. Biochem Biophys Res Commun. 2001 Jul 6; 285(1):15-9.
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  122. Baker JE, Contney SJ, Singh R, Kalyanaraman B, Gross GJ, Bosnjak ZJ. Nitric oxide activates the sarcolemmal K(ATP) channel in normoxic and chronically hypoxic hearts by a cyclic GMP-dependent mechanism. J Mol Cell Cardiol. 2001 Feb; 33(2):331-41.
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  123. Sato J, Singh RJ, I'Brien T, Katusic ZS, Fu A, Nygren JA, Nair KS. Dietary antioxidants preserve endothelium dependent vasorelaxation in obese rats. Clin Chem Part 2, Suppl S. 2000 Jun; 46(6):398.
  124. Goss SP, Singh RJ, Hogg N, Kalyanaraman B. Reactions of *NO, *NO2 and peroxynitrite in membranes: physiological implications. Free Radic Res Review. 1999 Dec; 31(6):597-606.
  125. Ferguson E, Hogg N, Antholine WE, Joseph J, Singh RJ, Parthasarathy S, Kalyanaraman B. Characterization of the adduct formed from the reaction between homocysteine thiolactone and low-density lipoprotein: antioxidant implications. Free Radic Biol Med. 1999 Apr; 26(7-8):968-77.
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  126. Singh RJ, Hogg N, Joseph J, Konorev E, Kalyanaraman B. The peroxynitrite generator, SIN-1, becomes a nitric oxide donor in the presence of electron acceptors. Arch Biochem Biophys. 1999 Jan 15; 361(2):331-9.
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  127. Singh RJ, Hogg N, Goss SP, Antholine WE, Kalyanaraman B. Mechanism of superoxide dismutase/H2O2-mediated nitric oxide release from S-nitrosoglutathione--Role of glutamate. Arch Biochem Biophys. 1999; 372:8-15.
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  128. Janssen YM, Soultanakis R, Steece K, Heerdt E, Singh RJ, Joseph J, Kalyanaraman B. Depletion of nitric oxide causes cell cycle alterations, apoptosis, and oxidative stress in pulmonary cells. Am J Physiol. 1998 Dec; 275(6 Pt 1):L1100-9.
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  129. Singh RJ, Goss SP, Joseph J, Kalyanaraman B. Nitration of gamma-tocopherol and oxidation of alpha-tocopherol by copper-zinc superoxide dismutase/H2O2/NO2-: role of nitrogen dioxide free radical. Proc Natl Acad Sci U S A. 1998 Oct 27; 95(22):12912-7.
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  130. Singh RJ, Karoui H, Gunther MR, Beckman JS, Mason RP, Kalyanaraman B. Reexamination of the mechanism of hydroxyl radical adducts formed from the reaction between familial amyotrophic lateral sclerosis-associated Cu,Zn superoxide dismutase mutants and H2O2. Proc Natl Acad Sci U S A. 1998 Jun 9; 95(12):6675-80.
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  131. Ferguson E, Singh RJ, Hogg N, Kalyanaraman B. The mechanism of apolipoprotein B-100 thiol depletion during oxidative modification of low-density lipoprotein. Arch Biochem Biophys. 1997 May 15; 341(2):287-94.
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  132. Hogg N, Singh RJ, Konorev E, Joseph J, Kalyanaraman B. S-Nitrosoglutathione as a substrate for gamma-glutamyl transpeptidase. Biochem J 323 ( 1997 Apr 15; Pt 2):477-81.
  133. Kalyanaraman B, Karoui H, Singh RJ, Felix CC. Detection of thiyl radical adducts formed during hydroxyl radical- and peroxynitrite-mediated oxidation of thiols--a high resolution ESR spin-trapping study at Q-band (35 GHz). Anal Biochem 1 1996 Oct; 241(1):75-81.
  134. Singh RJ, Hogg N, Joseph J, Kalyanaraman B. Mechanism of nitric oxide release from S-nitrosothiols. J of Biol Chem 2 1996 Aug; 271(31):18596-603.
  135. Hogg N, Singh RJ, Goss SP, Kalyanaraman B. The reaction between nitric oxide and alpha-tocopherol: a reappraisal. Biochem Biophys Res Commun. 1996 Jul 25; 224(3):696-702.
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  136. Hogg N, Singh RJ, Kalyanaraman B. The role of glutathione in the transport and catabolism of nitric oxide. FEBS Lett. 1996 Mar 18; 382(3):223-8.
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  137. Singh RJ, Hogg N, Kalyanaraman B. Interaction of nitric oxide with photoexcited rose bengal: evidence for one-electron reduction of nitric oxide to nitroxyl anion. Arch Biochem Biophys. 1995 Dec 20; 324(2):367-73.
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  138. Singh RJ, Feix JB, Mchaourab HS, Hogg N, Kalyanaraman B. Spin-labeling study of the oxidative damage to low-density lipoprotein. Arch Biochem Biophys. 1995 Jun 20; 320(1):155-61.
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  139. Singh RJ, Hogg N, Neese F, Joseph J, Kalyanaraman B. Trapping of nitric oxide formed during photolysis of sodium nitroprusside in aqueous and lipid phases: an electron spin resonance study. Photochem Photobiol. 1995 Apr; 61(4):325-30.
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  140. Singh RJ, Hogg N, Joseph J, Kalyanaraman B. Photosensitized decomposition of S-nitrosothiols and 2-methyl-2-nitrosopropane. Possible use for site-directed nitric oxide production. FEBS Lett. 1995 Feb 20; 360(1):47-51.
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  141. Hogg N, Singh RJ, Joseph J, Neese F, Kalyanaraman B. Reactions of nitric oxide with nitronyl nitroxides and oxygen: prediction of nitrite and nitrate formation by kinetic simulation. Free Radic Res. 1995 Jan; 22(1):47-56.
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  142. Singh RJ, Hogg N, Mchaourab HS, Kalyanaraman B. Physical and chemical interactions between nitric oxide and nitroxides. Biochem Biophys Acta. 1994 Dec 15; 1201(3):437-41.
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  143. Sidhu MS, Bhatia PVK, Singh RJ. Photochemical reduction of uranyl ion with triarylphosphite in acetone. J Radioanal Nucl Chem Lett. 1994; 188(5):355-65.
  144. Sidhu MS, Bhatia PVK, Singh RJ. A facile approach to measure the bimolecular quenching constant for quenching the optically excited dioxouranium (VI) ion. Proc Nat Acad Sci India. 1994; 64:656-660.
  145. Kalyanaraman B, Ramanujam S, Singh RJ, Joseph J, Feix JB. Formation of 2,5-Dihydroxybenzoic acid during the reaction between O2 and salicylic acid: Analysis by ESR Oximetry and HPLC with electrochemical detection J Am Chem Soc. 1993; 115:4007-4012.
  146. Sidhu MS, Chahal P, Singh RJ. Quenching of excited uranyl ion during its photochemical reduction by triphenylphosphine: part III. Indian J Chem. 1993; 32A:517-20.
  147. Singh RJ, Feix JB, Kalyanaraman B. Photobleaching of merocyanine 540: involvement of singlet molecular oxygen. Photochem Photobiol. 1992 Apr; 55(4):483-9.
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  148. O'Brien JM, Singh RJ, Feix JB, Kalyanaraman B, Sieber F. Action spectra of the antileukemic and antiviral activities of merocyanine 540. Photochem Photobiol. 1991 Nov; 54(5):851-4.
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  149. Singh RJ, Feix JB, Pintar TJ, Girotti AW, Kalyanaraman B. Photodynamic action of merocyanine 540 in artificial bilayers and natural membranes: action spectra and quantum yields. Photochem Photobiol. 1991 Apr; 53(4):493-500.
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  150. Sandhu SS, Singh RJ, Chawla SK. Uranium (V) as an intermediate in the photochemical reduction of uranyl ion with dicyclohexylsulphide. J Photochem Photobiol A: Chemistry. 1990; 52:65-68.
  151. Sidhu MS, Singh RJ, Sandhu SS. A new method for the evaluation physical bimolecular deactivation constants. J Chem Edu. 1990; 67:622.
  152. Sidhu MS, Singh RJ, Sarkaria P, Sandhu SS. Effect of aromatic molecules on the photochemical reduction of uranyl ion with triphenylphosphine. J Photochem Photobiol. 1989; 46:221-6.
  153. Sandhu SS, Sidhu MS, Singh RJ. Photochemical reduction of uranyl ion with trimethylphosphite. J Photochem Photobiol A: Chemistry. 1989; 46:213-219.
  154. Sandhu SS, Sidhu MS, Singh RJ. Luminescence study of uranyl trimethylacetate.dihydrate and Stern-Volmer quenching constants with various substrates in dry and aqueous acetone. J Photochem Photobiol. 1988; 42:251-59.
  155. Sandhu SS, Sidhu MS, Singh RJ. Study of the photoreduction of uranyl ion by triphenylphosphine, triphenylarsine, tri-p-tolylphosphine and tri-p-tolylarsine in acetone. J Photochem Photobiol. 1987; 39:229-37.