Smart Deep Brain Stimulation

The Neural Engineering Laboratory's Smart Deep Brain Stimulation (DBS) Team is working on creating software and algorithms to effectively manage the recording-stimulation feedback loop necessary for a closed-loop DBS system.

Meet the team

  • J. Luis Lujan, M.S., Ph.D.
    • Project Leader
    • Dr. Lujan is a biomedical engineer with a background in novel functional electrical stimulation to restore motor function in patients with spinal cord injuries. Dr. Lujan's project team is developing computational and mathematical modeling techniques to analyze the effects of deep brain stimulation with the goal of producing a closed-loop DBS control algorithm.
  • Leonardo (Leo) Espin, Ph.D.
    • Senior Engineer
    • Dr. Espin is an applied mathematician with a background in mathematical modeling and computational fluid dynamics. His research involves building mathematical models from first principles and studying them to advance and provide support to DBS technology.
  • Hyung Ook Park, Ph.D.
    • Senior Engineer
    • Dr. Park earned his Bachelor of Science and Master of Science in electrical engineering and his doctorate in biomedical engineering from the University of Southern California (USC). He completed a postdoctoral fellowship in the Laboratory for Neural Dynamics at USC and then came to the Mayo Clinic Neural Engineering Laboratory in 2015 to study the closed-loop control of deep brain stimulation with the Smart DBS Project team.
  • James K. Trevathan
    • Doctoral Student
    • James Trevathan earned his bachelor's degree in physics from Gustavus Adolphus College and is currently a candidate in the Biomedical Engineering and Physiology track of the Ph.D. Program at Mayo Graduate School. His interests are on the development and implementation of closed-loop neuromodulation therapies. In particular, his research involves using real-time electrochemical monitoring of neurotransmitters as a feedback signal for deep brain stimulation.
  • Seungleal (Brian) Paek
    • Doctoral Student
    • Brian Paek earned his Bachelor of Science in biochemistry and cell biology from the University of California, San Diego. He is currently pursuing his doctorate through the Mayo Graduate School. His primary research efforts focus on studying the underlying mechanisms of deep brain stimulation for neurological diseases.
  • Aiyana D. Batton
    • Postbaccalureate Research Education Program (PREP) Student
    • Aiyana Batton graduated with honors with a Bachelor of Science in biology from Spelman College. She then joined the Neural Engineering Laboratory to gain a better understanding of deep brain stimulation. She is conducting behavioral analyses on hemiparkinson rats and intends to apply to graduate schools in the coming year.